Clinical outcome after 450 revascularization procedures for moyamoya disease

R Guzman, M Lee, A Achrol, T Bell-Stephens… - Journal of …, 2009 - thejns.org
Object Moyamoya disease (MMD) is a rare cerebrovascular disease mainly described in the
Asian literature. To address a lack of data on clinical characteristics and long-term …

Expression of the int-1 gene in transgenic mice is associated with mammary gland hyperplasia and adenocarcinomas in male and female mice

AS Tsukamoto, R Grosschedl, RC Guzman, T Parslow… - Cell, 1988 - cell.com
Transcriptional activation of the in&l gene by proviral insertion mutations is thought to be a key
step in mammary tumor induction by the mouse mammary tumor virus (MMTV). To test this …

Cell transplantation therapy for stroke

T Bliss, R Guzman, M Daadi, GK Steinberg - Stroke, 2007 - Am Heart Assoc
No treatment currently exists to restore lost neurological function after stroke. A growing
number of studies highlight the potential of stem cell transplantation as a novel therapeutic …

The 16-kilodalton N-terminal fragment of human prolactin is a potent inhibitor of angiogenesis

C Clapp, JA Martial, RC Guzman… - …, 1993 - academic.oup.com
The formation of a new blood supply, angiogenesis, is an essential component of carcinogenesis
and unrestricted tumor growth. A substance capable of inhibiting angiogenesis would …

Hormones and mammary carcinogenesis in mice, rats, and humans: a unifying hypothesis.

S Nandi, RC Guzman, J Yang - Proceedings of the National …, 1995 - National Acad Sciences
An attempt has been made to put forward a unifying hypothesis explaining the role hormones
play in the genesis of mammary cancers of different phenotypes and genotypes in mice, …

Long-term monitoring of transplanted human neural stem cells in developmental and pathological contexts with MRI

R Guzman, N Uchida, TM Bliss, D He… - Proceedings of the …, 2007 - National Acad Sciences
Noninvasive monitoring of stem cells, using high-resolution molecular imaging, will be
instrumental to improve clinical neural transplantation strategies. We show that labeling of human …

Thrombospondins 1 and 2 are necessary for synaptic plasticity and functional recovery after stroke

…, T Bliss, RG Guzman… - Journal of Cerebral …, 2008 - journals.sagepub.com
Thrombospondins 1 and 2 (TSP-1/2) belong to a family of extracellular glycoproteins with
angiostatic and synaptogenic properties. Although TSP-1/2 have been postulated to drive the …

Neural progenitor cells regulate microglia functions and activity

…, M Hasegawa-Moriyama, Y He, R Guzman… - Nature …, 2012 - nature.com
We found mouse neural progenitor cells (NPCs) to have a secretory protein profile distinct
from other brain cells and to modulate microglial activation, proliferation and phagocytosis. …

Quantitative hemodynamic studies in moyamoya disease: a review

M Lee, G Zaharchuk, R Guzman, A Achrol… - Neurosurgical …, 2009 - thejns.org
Moyamoya disease is characterized by a chronic stenoocclusive vasculopathy affecting the
terminal internal carotid arteries. The clinical presentation and outcome of moyamoya …

Weanling piglet cerebellum: a surrogate for tolerance to MRT (microbeam radiation therapy) in pediatric neuro-oncology

…, DN Slatkin, N Lyubimova, R Guzman… - … and Applications III, 2001 - spiedigitallibrary.org
The cerebellum of the weanling piglet (Yorkshire) was used as a surrogate for the radiosensitive
human infant cerebellum in a Swiss-led program of experimental microbeam radiation …