Apert syndrome is a distinctive human malformation comprising craniosynostosis and
severe syndactyly of the hands and feet. We have identified specific missense substitutions …

✓ Seventy-five children treated for craniopharyngioma between 1973 and 1994 were studied
to demonstrate which pre- and intraoperative factors were indicative of a poor outcome as …

Salmonella causes severe gastroenteritis in humans, entering non‐phagocytic cells to
initiate intracellular replication. Bacterial engulfment occurs by macropinocytosis, which is …

✓ The aim of this study was to find reasons for the high incidence of cerebrospinal fluid shunt
infections seen in neonates. Four-hundred sixty-six consecutive shunt operations were …

The indications for surgical correction of craniosynostosis in which there is involvement of
only one of the cranial vault sutures have traditionally been based upon the cosmetic merits of …

Pathogen-induced remodelling of the host cell actin cytoskeleton drives internalization of
invasive Salmonella by non-phagocytic intestinal epithelial cells. Two Salmonella actin-binding …

CRANIOSYNOSTOSIS MANAGEMENT PARTIALLY depends on the detection and treatment
of elevated intracranial pressure (ICP). Examination for papilledema is considered to be the …

The growth and endocrine sequelae of 75 children (33 girls and 42 boys) with craniopharyngioma,
treated from 1973 to 1994, were studied by retrospective review and by follow up …

Salmonellae employ two type III secretion systems (T3SSs), SPI1 and SPI2, to deliver virulence
effectors into mammalian cells. SPI1 effectors, including actin-binding SipA, trigger initial …

Object. In this study the authors investigated whether patterns of intracranial venous drainage
in children with complex craniosynostosis associated with raised intracranial pressure (ICP…