Validation of functional diffusion maps (fDMs) as a biomarker for human glioma cellularity

BM Ellingson, MG Malkin, SD Rand… - Journal of Magnetic …, 2010 - Wiley Online Library
Purpose: To present comprehensive examinations of the assumptions made in functional
diffusion map (fDM) analyses and provide a biological basis for fDM classification. Materials …

Utility of simultaneously acquired gradient‐echo and spin‐echo cerebral blood volume and morphology maps in brain tumor patients

KM Donahue, HGJ Krouwer, SD Rand… - Magnetic resonance …, 2000 - Wiley Online Library
… [1] was determined from the average of all pixel values in a given image that did not demonstrate
steady-state signal enhancement greater than 1 SD above the pixel's average baseline …

Characterization of a first-pass gradient-echo spin-echo method to predict brain tumor grade and angiogenesis

KM Schmainda, SD Rand, AM Joseph… - American Journal …, 2004 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: No widespread clinical method provides specific information
about the angiogenic characteristics of gliomas. We characterized blood volume and …

Dynamic-susceptibility contrast agent MRI measures of relative cerebral blood volume predict response to bevacizumab in recurrent high-grade glioma

KM Schmainda, M Prah, J Connelly, SD Rand… - Neuro …, 2014 - academic.oup.com
Background The anti-VEGF antibody, bevacizumab, is standard treatment for patients with
recurrent glioblastoma. In this setting, traditional anatomic MRI methods such as post-contrast …

Initial experience of FDG-PET/CT guided IMRT of head-and-neck carcinoma

…, M Bialkowski, XR Zhu, WD Brown, SD Rand… - International Journal of …, 2006 - Elsevier
Purpose: The purpose of this study is to evaluate the impact of 18 F-fluorodeoxyglucose
positron emission tomography (FDG-PET) fused with planning computed tomography (CT) on …

Magnetic resonance imaging-based radiomic profiles predict patient prognosis in newly diagnosed glioblastoma before therapy

…, AL Kaczmarowski, EJ Cochran, J Connelly, SD Rand… - Tomography, 2016 - mdpi.com
Magnetic resonance imaging (MRI) is used to diagnose and monitor brain tumors. Extracting
additional information from medical imaging and relating it to a clinical variable of interest is …

Direct measurements of tetraphenylethylene torsional motion by picosecond spectroscopy

PF Barbara, SD Rand… - Journal of the American …, 1981 - ACS Publications
We have investigated the time-and wavelength-resolved fluorescence of tetraphenylethylene
(TPE) induced by 355-nm picosecond excitation in several solvents over a range of …

Precise ex vivo histological validation of heightened cellularity and diffusion-restricted necrosis in regions of dark apparent diffusion coefficient in 7 cases of high …

…, NJ Mickevicius, EJ Cochran, SD Rand… - Neuro …, 2014 - academic.oup.com
Background Recent conflicting reports have found both brain tumor hypercellularity and
necrosis in regions of restricted diffusion on MRI-derived apparent diffusion coefficient (ADC) …

Sample size calculation for clinical trials using magnetic resonance imaging for the quantitative assessment of carotid atherosclerosis

…, W Insull Jr, JD Morrisett, SD Rand… - Journal of …, 2005 - Taylor & Francis
Purpose. To provide sample size calculation for the quantitative assessment of carotid
atherosclerotic plaque using non-invasive magnetic resonance imaging in multi-center clinical …

Progressing bevacizumab-induced diffusion restriction is associated with coagulative necrosis surrounded by viable tumor and decreased overall survival in patients …

…, CJ Schultz, WM Mueller, SD Rand… - American Journal …, 2016 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Patients with recurrent glioblastoma often exhibit regions
of diffusion restriction following the initiation of bevacizumab therapy. Studies suggest that …