Objective. —A consensus conference on the diagnosis and treatment of Alzheimer disease (AD)
and related disorders was organized by the American Association for Geriatric …

The neuropsychologic test battery from the Uniform Data Set (UDS) of the Alzheimer's Disease
Centers (ADC) program of the National Institute on Aging consists of brief measures of …

Alzheimer’s disease is characterized by progressively worsening deficits in several cognitive
domains, including language. Language impairment in Alzheimer’s disease primarily …

The Alzheimer Disease Genetics Consortium (ADGC) performed a genome-wide association
study of late-onset Alzheimer disease using a three-stage design consisting of a discovery …

We examine the number of external appointments held by corporate directors. Directors who
serve larger firms and sit on larger boards are more likely to attract directorships. Consistent …

Background Mild cognitive impairment is a transitional state between the cognitive changes
of normal aging and early Alzheimer's disease. Methods In a double-blind study, we …

Background Bapineuzumab, a humanized anti–amyloid-beta monoclonal antibody, is in
clinical development for the treatment of Alzheimer's disease. Methods We conducted two …

Cognitive decline associated with old age and consistent with the diagnosis of primary
degenerative dementia is a unique clinical syndrome with characteristic phenomena and …

Background Overstimulation of the N-methyl-D-aspartate (NMDA) receptor by glutamate is
implicated in neurodegenerative disorders. Accordingly, we investigated memantine, an …

Limited information is available regarding the incidence, nature, and treatment of behavioral
problems in Alzheimer's disease (AD). A chart review of 57 outpatients with a diagnosis of …