Targeting AMPK: a new therapeutic opportunity in breast cancer
SM Hadad, S Fleming, AM Thompson - Critical reviews in oncology …, 2008 - Elsevier
BACKGROUND: This paper reviews the mammalian Target Of Rapamycin (mTOR) pathway
dysregulation in breast cancer, and the current evidence targeting this pathway directly or …
dysregulation in breast cancer, and the current evidence targeting this pathway directly or …
[PDF][PDF] Metformin promotes antitumor immunity via endoplasmic-reticulum-associated degradation of PD-L1
… However, the functions and detailed mechanisms of metformin’s role in cancer immunity
are not fully understood. Here, we show that metformin increases CTL activity by reducing the …
are not fully understood. Here, we show that metformin increases CTL activity by reducing the …
Evidence for biological effects of metformin in operable breast cancer: a pre-operative, window-of-opportunity, randomized trial
Metformin may reduce the incidence of breast cancer and enhance response to neoadjuvant
chemotherapy in diabetic women. This trial examined the effects of metformin on Ki67 and …
chemotherapy in diabetic women. This trial examined the effects of metformin on Ki67 and …
Intermediate and long-term outcomes of total ankle arthroplasty and ankle arthrodesis: a systematic review of the literature
SL Haddad, JC Coetzee, R Estok, K Fahrbach, D Banel… - JBJS, 2007 - journals.lww.com
Background: The efficacy of total ankle replacement compared with that of ankle fusion
continues to be one of the most debated topics in foot and ankle surgery. The purpose of this …
continues to be one of the most debated topics in foot and ankle surgery. The purpose of this …
Determinants of healthcare system's efficiency in OECD countries
Objective Firstly, to compare healthcare systems’ efficiency (HSE) using two models: one
incorporating mostly inputs that are considered to be within the discretionary control of the …
incorporating mostly inputs that are considered to be within the discretionary control of the …
[HTML][HTML] Critical care management of severe traumatic brain injury in adults
Traumatic brain injury (TBI) is a major medical and socio-economic problem, and is the leading
cause of death in children and young adults. The critical care management of severe TBI …
cause of death in children and young adults. The critical care management of severe TBI …
Knowledge economy: Characteristics and dimensions
S Hadad - Management dynamics in the Knowledge economy, 2017 - ceeol.com
Over the past several decades, the theme of knowledge economy (KE) has become
increasingly important, being seen as a source of economic growth and competitiveness in all …
increasingly important, being seen as a source of economic growth and competitiveness in all …
[HTML][HTML] Histological evaluation of AMPK signalling in primary breast cancer
Background AMP-activated protein kinase (AMPK) acts as a cellular fuel gauge that responds
to energy stress by suppressing cell growth and biosynthetic processes, thus ensuring that …
to energy stress by suppressing cell growth and biosynthetic processes, thus ensuring that …
Eradication of carbapenem-resistant Enterobacteriaceae gastrointestinal colonization with nonabsorbable oral antibiotic treatment: a prospective controlled trial
I Oren, H Sprecher, R Finkelstein, S Hadad… - American journal of …, 2013 - Elsevier
Background Carbapenem-resistant Enterobacteriaceae (CRE) are emerging. In attempt to
eradicate CRE colonization, we conducted a semirandomized, prospective, controlled trial …
eradicate CRE colonization, we conducted a semirandomized, prospective, controlled trial …
[PDF][PDF] Developing software for multi-access edge computing
…, L Cominardi, W Featherstone, B Pike, S Hadad - ETSI white …, 2019 - cloud.report
… (s), edge component(s) and remote component(s). This concept should not be confused
with the traditional software modularization, but rather seen as a distribution of components to …
with the traditional software modularization, but rather seen as a distribution of components to …
