… X is a compound with an electrophilic center that can form GSH conjugate in a reaction
catalyzed by GSH S-transferase. The γ-glutamyl moiety is then cleaved by γ-…

… Organic peroxides can also be reduced by GPx and GSH S-transferase. Catalase can also
reduce hydrogen peroxide but it is present only in peroxisome. This makes GSH particularly …

… To achieve the best flame retardancy rating of V0, the burning must stop within 10 s after
two applications of 10 s each of a flame to a test bar and no flaming drips are allowed. …

Background During the spring of 2013, a novel avian-origin influenza A (H7N9) virus emerged
and spread among humans in China. Data were lacking on the clinical characteristics of …

The genomes of cancers deficient in mismatch repair contain exceptionally high numbers of
somatic mutations. In a proof-of-concept study, we previously showed that colorectal …

This paper presents a brief synthesis of the current state of knowledge on the formation and
break-up of the early-Neoproterozoic supercontinent Rodinia, and the subsequent assembly …

Background No therapeutics have yet been proven effective for the treatment of severe
illness caused by SARS-CoV-2. Methods We conducted a randomized, controlled, open-label …

NCBI’s Conserved Domain Database (CDD) is a resource for the annotation of protein
sequences with the location of conserved domain footprints, and functional sites inferred from …

Background Neoadjuvant or adjuvant chemotherapy confers a modest benefit over surgery
alone for resectable non–small-cell lung cancer (NSCLC). In early-phase trials, nivolumab-…

Background Activating mutations in EGFR are important markers of response to tyrosine
kinase inhibitor (TKI) therapy in non-small-cell lung cancer (NSCLC). The OPTIMAL study …