User profiles for S. Shibata

Shinsuke Shibata

Verified email at keio.jp
Cited by 9637

Chemistry and cancer preventing activities of ginseng saponins and some related triterpenoid compounds.

S Shibata - Journal of Korean medical science, 2001 - ncbi.nlm.nih.gov
… finally 20(S)-protopanaxadiol. Ginsenoside Rg-1 was converted into 20(S)-protopanaxatriol …
proved to be 20(S)12 hydroxy- and 20(S) 6 ,12 -dihydroxy-dammarenediol-II, respectively. …

A drug over the millennia: pharmacognosy, chemistry, and pharmacology of licorice

S Shibata - Yakugaku zasshi, 2000 - jstage.jst.go.jp
… In 1951, Green et (11.13) noted that licorice extract or GL is effective for minimal Addison’s
disease, but ineffective for severe cases and that GL is ineffective in adrenalectomized rats”) …

Function of RNA-binding protein Musashi-1 in stem cells

…, H Kawahara, M Toriya, K Nakao, S Shibata… - Experimental cell …, 2005 - Elsevier
… Future research study will elucidate the precise molecular mechanisms by which these
mammalian MUSASHI proteins regulate the translation of their target mRNA(s), and their link to …

Highly enantioselective borane reduction of ketones catalyzed by chiral oxazaborolidines. Mechanism and synthetic implications

EJ Corey, RK Bakshi, S Shibata - Journal of the American …, 1987 - ACS Publications
… (6) (S)-… The (S)-diphenylprolinol obtained in this way, mp 74.0-74.8 C, [a]D22 -68.1 (c
3.17 in CHC13), had 99.0% ee as shown by conversion to the corresponding MTPA amide ((S)-(+)-…

[HTML][HTML] Light-induced resetting of a mammalian circadian clock is associated with rapid induction of the mPer1 transcript

…, S Takekida, L Yan, H Tei, T Moriya, S Shibata… - Cell, 1997 - cell.com
To understand how light might entrain a mammalian circadian clock, we examined the effects
of light on mPer1, a sequence homolog of Drosophila per, that exhibits robust rhythmic …

A stable and easily prepared catalyst for the enantioselective reduction of ketones. Applications to multistep syntheses

EJ Corey, RK Bakshi, S Shibata… - Journal of the …, 1987 - ACS Publications
We have recently described a new method for the catalytic enantioselective reduction of
ketones to chiral secondary alcohols. 1 The stoichiometric reagent in the reduction is borane (…

Novel bile acid biosynthetic pathways are enriched in the microbiome of centenarians

…, Y Sugiura, M Suematsu, N Moritoki, S Shibata… - Nature, 2021 - nature.com
Centenarians have a decreased susceptibility to ageing-associated illnesses, chronic
inflammation and infectious diseases 1, 2, 3. Here we show that centenarians have a distinct gut …

[HTML][HTML] Mechanical properties of biodegradable composites reinforced with bagasse fibre before and after alkali treatments

Y Cao, S Shibata, I Fukumoto - Composites part A: Applied science and …, 2006 - Elsevier
Biodegradable composites reinforced with bagasse fibre before and after alkali treatments
were prepared, and mechanical properties were investigated. Mechanical properties of the …

A high-resolution structure of the pre-microRNA nuclear export machinery

C Okada, E Yamashita, SJ Lee, S Shibata, J Katahira… - Science, 2009 - science.org
Nuclear export of microRNAs (miRNAs) by exportin-5 (Exp-5) is an essential step in miRNA
biogenesis. Here, we present the 2.9 angstrom structure of the pre-miRNA nuclear export …

Restricted feeding entrains liver clock without participation of the suprachiasmatic nucleus

…, R Aida, T Moriya, M Akiyama, S Shibata - Genes to …, 2001 - Wiley Online Library
… A lesion was created by maintaining a temperature of 55 C for 15 s using a current path,
and sham-operated animals were created using a noncurrent path. After surgery, the animals …