[HTML][HTML] Bcl-2 family: life-or-death switch

Y Tsujimoto, S Shimizu - FEBS letters, 2000 - Elsevier
… Kroemer’s group has described that Bax modulates ANT activity [44], although how Bax
actually induces cytochrome c release by interacting with ANT was not sufficiently explained. It …

[HTML][HTML] Another way to die: autophagic programmed cell death

Y Tsujimoto, S Shimizu - Cell Death & Differentiation, 2005 - nature.com
… understand the pathology and the potential therapeutic strategies for human diseases
that are characterized by enhanced cell death, it is crucial to elucidate the death mechanism(s) …

Role of the mitochondrial membrane permeability transition in cell death

Y Tsujimoto, S Shimizu - Apoptosis, 2007 - Springer
… This finding suggests that ANT1/2 only play a limited role, if any, in the MPT or else that
deficiency of ANT1/2 was compensated by other channel(s). The lack of an important role for the …

Phylogenomics resolves the timing and pattern of insect evolution

…, BM Von Reumont, K Schütte, K Sekiya, S Shimizu… - Science, 2014 - science.org
Insects are the most speciose group of animals, but the phylogenetic relationships of many
major lineages remain unresolved. We inferred the phylogeny of insects from 1478 protein-…

Prevention of hypoxia-induced cell death by Bcl-2 and Bcl-xL

S Shimizu, Y Eguchi, H Kosaka, W Kamiike, H Matsuda… - Nature, 1995 - nature.com
… Western blotting was performed using mouse anti-human Bcl-2 monoclonal antibody",
and rabbit anti-chicken Bcl-x polyclonal antibody that was raised against glutathione S-…

Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC

S Shimizu, M Narita, Y Tsujimoto, Y Tsujimoto - Nature, 1999 - nature.com
… VDAC purified from rat liver mitochondria efficiently bound to a fusion protein between
glutathione-S -transferase and Bcl-x L (GST–Bcl-x L ), however, indicating that Bcl-x L interacted …

Molecular cloning and expression of human hepatocyte growth factor

…, M Shimonishi, A Sugimura, K Tashiro, S Shimizu - Nature, 1989 - nature.com
… An interchain SS bridge is indicated by asterisks. Dotted underlines indicate the kringle …
The difference between the M, s of the HGF subunits as determined by SDS-PAGE and those …

Primary structure of Electrophorus electricus sodium channel deduced from cDNA sequence

M Noda, S Shimizu, T Tanabe, T Takai, T Kayano… - Nature, 1984 - nature.com
S 4 – – S5 Favoured amino acid substitutions are defined as pairs of residues belonging to
| ||F|MGN | R || - KICI R / P [|SNy-T|_|-) YE|–(53)–f|YDNF A WTF LICILE ::::: ---- 255.- 383 one …

Discovery of Atg5/Atg7-independent alternative macroautophagy

…, M Komatsu, K Otsu, Y Tsujimoto, S Shimizu - Nature, 2009 - nature.com
… cRNA was hybridized to Mouse Whole Genome 4 × 44K microarrays (Agilent Technologies)
in accordance with the manufacturer’s instructions. Two biological replicates were …

Role of Bcl-2 family proteins in a non-apoptotic programmed cell death dependent on autophagy genes

S Shimizu, T Kanaseki, N Mizushima, T Mizuta… - Nature cell …, 2004 - nature.com
Programmed cell death can be divided into several categories including type I (apoptosis)
and type II (autophagic death) 1 , 2 . The Bcl-2 family of proteins are well-characterized …