During animal fertilizations, each oocyte or egg must produce a proper intracellular calcium
signal for development to proceed normally. As a supplement to recent synopses of …

Myriads of epigenomic features have been comprehensively profiled in health and disease
across cell types, tissues and individuals. Although current epigenomic approaches can infer …

Human brain tumors appear to have a hierarchical cellular organization suggestive of a
stem cell foundation. In vitro expansion of the putative cancer stem cells as stable cell lines …

… Altogether, they aim to describe the conformity of a person’s behaviour with that
recommended by their health-care provider(s). However, each word has a specific meaning and …

Cell size is determined by the balance between protein synthesis and degradation. This
equilibrium is affected by hormones, nutrients, energy levels, mechanical stress and cytokines. …

Mammalian imprinted genes often cluster with long noncoding (lnc) RNAs. Three lncRNAs
that induce parental-specific silencing show hallmarks indicating that their transcription is …

Fuhrmann syndrome and the Al-Awadi/Raas-Rothschild/Schinzel phocomelia syndrome are
considered to be distinct limb-malformation disorders characterized by various degrees of …

… Upon infection, children’s neutrophils showed an activated phenotype that was more
pronounced than in infected adults, characterized by the enhanced expression of, for example, …

Runx2/Cbfa1 plays a central role in skeletal development as demonstrated by the absence
of osteoblasts/bone in mice with inactivated Runx2/Cbfa1 alleles. To further investigate the …

Here we describe 2 mutations in growth and differentiation factor 5 (GDF5) that alter receptor-binding
affinities. They cause brachydactyly type A2 (L441P) and symphalangism (R438L), …