Gene silencing through RNA interference (RNAi) has revolutionized the study of gene function,
particularly in non-model insects. However, in Lepidoptera (moths and butterflies) RNAi …

Glutamate, the major excitatory neurotransmitter in the brain, acts primarily on two types of
ionotropic receptors: α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) …

A large proportion of biomedical research and the development of therapeutics is focused
on a small fraction of the human genome. In a strategic effort to map the knowledge gaps …

Background—Autologous bone marrow cells (BMCs) transplanted into ventricular scar
tissue may differentiate into cardiomyocytes and restore myocardial function. This study …

Cardiac hypertrophy occurs as an adaptive response to increased workload to maintain
cardiac function 1 . However, prolonged cardiac hypertrophy causes heart failure 2 , and its …

… and coronal sections of adult rat brain with 35 S-labeled antisense probes, which revealed
… S. Tomita is supported by a grant from Research Fellowships of the Japan Society for the …

… Moreover, Bombyx carries three sil genes, yet does not show a robust systemic RNAi
response (S Tomita, unpublished data; R Futahashi and T Kusakabe, personal communications). …

AMPA (α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid) receptors mediate fast
excitatory synaptic transmission in the brain. These ion channels rapidly deactivate and …

Previous studies have demonstrated that polyunsaturated fatty acids (PUFAs) suppress sterol
regulatory element-binding protein 1c (SREBP-1c) expression and, thus, lipogenesis. In …

… Tomita's parents, the late Susumu Tomita, and Hiroko Tomita, taught her the values that …
Tomita is extremely fortunate to have Cliff Barda and Jason RabbittTomita, who ran around and …