The Japanese Society of Hypertension (JSH) revised the Guidelines for the Management of
Hypertension 2014 (JSH 2014), and published the JSH 2019. In the development of the JSH …

Cellular redox is controlled by the thioredoxin (Trx) and glutathione (GSH) systems that
scavenge harmful intracellular reactive oxygen species (ROS). Oxidative stress also evokes …

BACKGROUND: A non-enzymatic reaction between reducing sugars and amino groups of
proteins, lipids and nucleic acids contributes to the aging of macromolecules, whose process …

We present a combined analysis of fully-contained, partially-contained and upward-going
muon atmospheric neutrino data from a 1489 d exposure of the Super-Kamiokande detector. …

Muon neutrino disappearance probability as a function of neutrino flight length L over neutrino
energy E was studied. A dip in the L / E distribution was observed in the data, as predicted …

Despite the therapeutic potential of nucleic acid drugs, their clinical application has been
limited in part by a lack of appropriate delivery systems. Exosomes or microvesicles are small …

… Kazuaki Shimamoto, Katsuyuki Ando, Toshiro Fujita, Naoyuki Hasebe, Jitsuo Higaki,
Masatsugu Horiuchi, Yutaka Imai, Tsutomu Imaizumi, Toshihiko Ishimitsu, Masaaki Ito …

Background—Exposure to risk factors such as hypertension or hypercholesterolemia
decreases the bioavailability of endothelium-derived nitric oxide (NO) and impairs endothelium-…

3. Morbidity and mortality rates due to diseases such as stroke, myocardial infarction, heart
disease and chronic renal disease increase with elevating blood pressure. The effects of …

We present results for ν μ oscillation in the KEK to Kamioka (K2K) long-baseline neutrino
oscillation experiment. K2K uses an accelerator-produced ν μ beam with a mean energy of 1.3 …