Ever since its remarkable mechanical properties were found fifteen years ago, interest has
grown in bacterial cellulose for which the use had been more or less limited to the …

Pluripotent stem cells, such as embryonic stem cells (ESCs), proliferate rapidly while
maintaining pluripotency, namely, the ability to differentiate into various types of cells. Embryonic …

… To overcome these issues, multiple groups have been trying to generate hESCs from a
patient’s own somatic cells by means of nuclear transfer. This strategy was popularized in 1996 …

… The identification of the missing factor(s) may enable more efficient and retrovirus-free
generation of iPS cells. Alternatively, iPS cell induction may depend on specific amounts and …

The stable states of differentiated cells are now known to be controlled by dynamic mechanisms
that can easily be perturbed. An adult cell can therefore be reprogrammed, altering its …

Successful reprogramming of differentiated human somatic cells into a pluripotent state
would allow creation of patient- and disease-specific stem cells. We previously reported …

Differentiated cells can be reprogrammed to an embryonic-like state by transfer of nuclear
contents into oocytes or by fusion with embryonic stem (ES) cells. Little is known about factors …

<p id="p001">We assessed the feasibility of transplanting a sheet of retinal pigment epithelial
(RPE) cells differentiated from induced pluripotent stem cells (iPSCs) in a patient with …

Induced pluripotent stem (iPS) cells have been generated from mouse and human somatic
cells by introducing Oct3/4 and Sox2 with either Klf4 and c-Myc or Nanog and Lin28 using …

Direct reprogramming of somatic cells provides an opportunity to generate patient- or
disease-specific pluripotent stem cells. Such induced pluripotent stem (iPS) cells were generated …