Paraneoplastic limbic encephalitis (PLE) is a rare disorder characterized by personality
changes, irritability, depression, seizures, memory loss and sometimes dementia. The diagnosis …

Object Cavernous malformations (CMs) of the optic pathway and hypothalamus (OPH) are
extremely rare. Patients with these lesions typically present with chiasmal apoplexy, …

Background In patients with cancer, symptoms of limbic and brain-stem dysfunction may
result from a paraneoplastic disorder. Paraneoplastic limbic or brain-stem encephalitis occurs …

The identification of antineuronal antibodies has facilitated the diagnosis of paraneoplastic
neurological disorders and the early detection of the associated tumours. It has also led to the …

Tumor-restricted surface antigens may be targets for diagnosis and immune-based therapies.
Monoclonal antibody 8H9 is a murine IgG1 hybridoma derived from the fusion of mouse …

We report a novel, proof-of-concept, computational method that models a type of brain cancer
(glioma) only by using the topological properties of its cells in the tissue image. From low-…

BACKGROUND AND PURPOSE: The insula is important for gustatory sensation, motor speech
control, vestibular function, and sympathetic control of cardiovascular tone. The purpose …

BACKGROUND AND PURPOSE: The laminar patterns displayed by MR microscopy (MRM)
form one basis for the classification of the cytoarchitectonic areas (Brodmann areas). It is …

Acromegaly is associated with serious morbidity and mortality, if not well controlled. Approved
somatostatin receptor ligands (SRLs) are a mainstay of medical therapy and exhibit …

Object Infantile and late-infantile neuronal ceroid lipofuscinoses (NCLs) are invariably fatal
lysosomal storage diseases associated with defects in lysosomal enzyme palmitoyl-protein …