Inherited Dysfunction of Sarcoplasmic Reticulum Ca2+ Handling and Arrhythmogenesis
… ) and opens the channel, leading to a large release of Ca 2+ from the SR, the major … , SR
Ca 2+ release is terminated, and the released Ca 2+ is recycled back to the SR by the SR Ca 2…
Ca 2+ release is terminated, and the released Ca 2+ is recycled back to the SR by the SR Ca 2…
[PDF][PDF] Regulation of spermatogonial stem cell self-renewal and spermatocyte meiosis by Sertoli cell signaling
SR Chen, YX Liu - 2015 - researchgate.net
… testicular cells isolated from mice around 2.5 days old, creating a functional ‘testis’ in vitro
which undergoes spermatogenesis to produce haploid sperm (Y Zhang, SL Deng, SR Chen, …
which undergoes spermatogenesis to produce haploid sperm (Y Zhang, SL Deng, SR Chen, …
[HTML][HTML] A Mechanistic Overview of Triptolide and Celastrol, Natural Products from Tripterygium wilfordii Hook F
Triptolide and celastrol are predominantly active natural products isolated from the medicinal
plant Tripterygium wilfordii Hook F. These compounds exhibit similar pharmacological …
plant Tripterygium wilfordii Hook F. These compounds exhibit similar pharmacological …
Neurologic involvement in children and adolescents hospitalized in the United States for COVID-19 or multisystem inflammatory syndrome
…, SV Lipton, AL Graciano, SR Chen… - JAMA …, 2021 - jamanetwork.com
Importance Coronavirus disease 2019 (COVID-19) affects the nervous system in adult
patients. The spectrum of neurologic involvement in children and adolescents is unclear. …
patients. The spectrum of neurologic involvement in children and adolescents is unclear. …
RyR2 mutations linked to ventricular tachycardia and sudden death reduce the threshold for store-overload-induced Ca2+ release (SOICR)
… , it is known that when SR Ca 2+ content reaches a critical level, spontaneous SR Ca 2+ …
the SR Ca 2+ store, we refer to this depolarization-independent Ca 2+ overload-induced SR …
the SR Ca 2+ store, we refer to this depolarization-independent Ca 2+ overload-induced SR …
The RCAF complex mediates chromatin assembly during DNA replication and repair
JK Tyler, CR Adams, SR Chen, R Kobayashi… - Nature, 1999 - nature.com
Chromatin assembly is a fundamental biological process that is essential for the replication
and maintenance of the eukaryotic genome 1 , 2 , 3 , 4 . In dividing cells, newly synthesized …
and maintenance of the eukaryotic genome 1 , 2 , 3 , 4 . In dividing cells, newly synthesized …
[HTML][HTML] Dantrolene inhibition of ryanodine receptor Ca2+ release channels: molecular mechanism and isoform selectivity
F Zhao, P Li, SRW Chen, CF Louis, BR Fruen - Journal of Biological …, 2001 - ASBMB
As an inhibitor of Ca 2+ release through ryanodine receptor (RYR) channels, the skeletal
muscle relaxant dantrolene has proven to be both a valuable experimental probe of …
muscle relaxant dantrolene has proven to be both a valuable experimental probe of …
Enhanced Store Overload–Induced Ca2+ Release and Channel Sensitivity to Luminal Ca2+ Activation Are Common Defects of RyR2 Mutations Linked to Ventricular …
…, DJ Hunt, P Choi, L Zhang, SRW Chen - Circulation …, 2005 - Am Heart Assoc
… This Ca 2+ influx then activates RyR2, resulting in a large Ca 2+ release from the SR and …
release, spontaneous SR Ca 2+ release via RyR2 can occur under the conditions of SR Ca 2+ …
release, spontaneous SR Ca 2+ release via RyR2 can occur under the conditions of SR Ca 2+ …
Ordered mesoporous carbon/sulfur nanocomposite of high performances as cathode for lithium–sulfur battery
Ordered mesoporous carbon/sulfur (OMC/S) nanocomposites with hierarchically structured
sulfur loading, ranging from 50 to 75wt%, were synthesized via a simple melt-diffusion …
sulfur loading, ranging from 50 to 75wt%, were synthesized via a simple melt-diffusion …
Carvedilol and its new analogs suppress arrhythmogenic store overload–induced Ca2+ release
Carvedilol is one of the most effective beta blockers for preventing ventricular tachyarrhythmias
in heart failure, but the mechanisms underlying its favorable antiarrhythmic benefits …
in heart failure, but the mechanisms underlying its favorable antiarrhythmic benefits …