Background Neuraminidase inhibitors were widely used during the 2009–10 influenza A H1N1
pandemic, but evidence for their effectiveness in reducing mortality is uncertain. We did a …

New rapid molecular diagnostic technologies for infectious diseases enable expedited
accurate microbiological diagnoses. However, diagnostic stewardship and antimicrobial …

This review highlights clinical features of the increasing cases of acute flaccid paralysis
associated with anterior myelitis noted in the United States from 2012 to 2015. Acute flaccid …

Background Metagenomic next-generation sequencing (NGS) of cerebrospinal fluid (CSF)
has the potential to identify a broad range of pathogens in a single test. Methods In a 1-year, …

Background: There are limited pediatric data regarding severe COVID-19 disease. Our study
aims to describe the epidemiology and identify risk factors for severe COVID-19 disease in …

Background Enterovirus D68 was implicated in a widespread outbreak of severe respiratory
illness across the USA in 2014 and has also been reported sporadically in patients with …

Background Clusters of acute flaccid paralysis or cranial nerve dysfunction in children are
uncommon. We aimed to assess a cluster of children with acute flaccid paralysis and cranial …

Little is known about the biology of the emerging human group c betacoronavirus, Middle
East Respiratory Syndrome coronavirus (MERS-CoV). Because coronavirus spike …

Increased circulation of enterovirus D68 in 2014 and 2016 temporally and geographically
coincided with increases in cases of acute flaccid myelitis, an uncommon condition of …

Background Enterovirus D68 (EV-D68) has been infrequently reported historically, and is
typically associated with isolated cases or small clusters of respiratory illness. Beginning in …