Randomized phase III study 306: adjunctive perampanel for refractory partial-onset seizures
…, SB Hong, JK Kang, SH Kim, SE Kim, BI Lee, SK Lee… - Neurology, 2012 - AAN Enterprises
Objective: To evaluate the efficacy and safety of perampanel 2, 4, and 8 mg/day added to 1–3
concomitant antiepileptic drugs (AEDs) in patients with uncontrolled partial-onset seizures. …
concomitant antiepileptic drugs (AEDs) in patients with uncontrolled partial-onset seizures. …
Anti-inflammatory mechanism of intravascular neural stem cell transplantation in haemorrhagic stroke
Neural stem cell (NSC) transplantation has been investigated as a means to reconstitute the
damaged brain after stroke. In this study, however, we investigated the effect on acute …
damaged brain after stroke. In this study, however, we investigated the effect on acute …
miR‐206 regulates brain‐derived neurotrophic factor in Alzheimer disease model
Objective: Alzheimer disease (AD) brains are deficient in brain‐derived neurotrophic factor (BDNF),
which regulates synaptic plasticity and memory. MicroRNAs (miRNAs) are ∼22‐…
which regulates synaptic plasticity and memory. MicroRNAs (miRNAs) are ∼22‐…
Surgical outcome and prognostic factors of cryptogenic neocortical epilepsy
Surgical treatment of cryptogenic neocortical epilepsy is challenging. The aim of this study
was to evaluate surgical outcomes and to identify possible prognostic factors including the …
was to evaluate surgical outcomes and to identify possible prognostic factors including the …
Cyclooxygenase-2 inhibitor, celecoxib, inhibits the altered hippocampal neurogenesis with attenuation of spontaneous recurrent seizures following pilocarpine …
Recent evidences suggest key roles of abnormal neurogenesis and astrogliosis in the
pathogenesis of epilepsy. Alterations in the microenvironment of the stem cell, such as microglial …
pathogenesis of epilepsy. Alterations in the microenvironment of the stem cell, such as microglial …
Altered microRNA regulation in Huntington's disease models
Huntington's disease (HD) is a genetic neurodegenerative disease caused by abnormal CAG
expansion. MicroRNAs (miRNAs) are short RNA molecules regulating gene expression, …
expansion. MicroRNAs (miRNAs) are short RNA molecules regulating gene expression, …
VGKC-complex/LGI1-antibody encephalitis: clinical manifestations and response to immunotherapy
…, KJ Lee, YS Kim, KI Park, KH Jung, SK Lee… - Journal of …, 2013 - Elsevier
Leucine-rich glioma inactivated 1 (LGI1) was recently identified as a target protein in
autoimmune synaptic encephalitis, a rare condition associated with autoantibodies against …
autoimmune synaptic encephalitis, a rare condition associated with autoantibodies against …
MicroRNAs induced during ischemic preconditioning
Background and Purpose— MicroRNAs (miRNA) are single-stranded short RNA molecules
that regulate gene expression by either degradation or translational repression of mRNA. …
that regulate gene expression by either degradation or translational repression of mRNA. …
Focal lesion in the splenium of the corpus callosum in epileptic patients: antiepileptic drug toxicity?
…, SW Jeong, MH Han, SK Lee - American journal …, 1999 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Discrete focal lesions in the splenium of the corpus
callosum on MR images in epileptic patients have received little attention in the literature. Our …
callosum on MR images in epileptic patients have received little attention in the literature. Our …
[HTML][HTML] Tocilizumab in autoimmune encephalitis refractory to rituximab: an institutional cohort study
A considerable portion of autoimmune encephalitis (AE) does not respond to conventional
immunotherapies and subsequently has poor outcomes. We aimed to determine the efficacy …
immunotherapies and subsequently has poor outcomes. We aimed to determine the efficacy …