User profiles for Sean B. Fain

Sean Fain

Professor of Radiology
Verified email at uiowa.edu
Cited by 10792

Inflammatory and comorbid features of patients with severe asthma and frequent exacerbations

…, M DeBoer, SC Erzurum, SB Fain… - American journal of …, 2017 - atsjournals.org
Rationale: Reducing asthma exacerbation frequency is an important criterion for approval of
asthma therapies, but the clinical features of exacerbation-prone asthma (EPA) remain …

[HTML][HTML] Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction

…, EA Hoffman, M Castro, SB Fain… - The Journal of …, 2018 - Am Soc Clin Investig
BACKGROUND. The link between mucus plugs and airflow obstruction has not been established
in chronic severe asthma, and the role of eosinophils and their products in mucus plug …

Optimized 3D ultrashort echo time pulmonary MRI

KM Johnson, SB Fain, ML Schiebler… - Magnetic resonance in …, 2013 - Wiley Online Library
Purpose To optimize 3D radial ultrashort echo time MRI for high resolution whole‐lung imaging.
Methods 3D radial ultrashort echo time was implemented on a 3T scanner to investigate …

PC VIPR: a high-speed 3D phase-contrast method for flow quantification and high-resolution angiography

T Gu, FR Korosec, WF Block, SB Fain… - American journal …, 2005 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Three-dimensional phase-contrast (3DPC) is limited by long
imaging times, limited coverage, flow artifacts, and the need to perform multiple additional …

Severe asthma: lessons learned from the national heart, lung, and blood institute severe asthma research program

…, D Curran-Everett, RA Dweik, SB Fain… - American journal of …, 2012 - atsjournals.org
The National Heart, Lung, and Blood Institute Severe Asthma Research Program (SARP) has
characterized over the past 10 years 1,644 patients with asthma, including 583 individuals …

Functional lung imaging using hyperpolarized gas MRI

SB Fain, FR Korosec, JH Holmes… - Journal of Magnetic …, 2007 - Wiley Online Library
The noninvasive assessment of lung function using imaging is increasingly of interest for
the study of lung diseases, including chronic obstructive pulmonary disease (COPD) and …

Early Emphysematous Changes in Asymptomatic Smokers: Detection with 3He MR Imaging1

SB Fain, SR Panth, MD Evans, AL Wentland… - Radiology, 2006 - pubs.rsna.org
Purpose: To prospectively compare apparent diffusion coefficient (ADC) measurements
derived from diffusion-weighted hyperpolarized helium 3 ( 3 He) magnetic resonance (MR) …

Effect of windowing and zero‐filled reconstruction of MRI data on spatial resolution and acquisition strategy

MA Bernstein, SB Fain… - Journal of magnetic …, 2001 - Wiley Online Library
Standard, MR spin‐warp sampling strategies acquire data on a rectangular k‐space grid.
That method samples data from the “corners” of k‐space, ie, data that lie in a region of k‐space …

Evaluation of structure-function relationships in asthma using multidetector CT and hyperpolarized He-3 MRI

SB Fain, G Gonzalez-Fernandez, ET Peterson… - Academic radiology, 2008 - Elsevier
RATIONALE AND OBJECTIVES: Although multiple detector computed tomography (MDCT)
and hyperpolarized gas magnetic resonance imaging (HP MRI) have demonstrated ability to …

Assessment of Acute Renal Transplant Rejection with Blood Oxygen Level–Dependent MR Imaging: Initial Experience1

EA Sadowski, SB Fain, SK Alford, FR Korosec, J Fine… - Radiology, 2005 - pubs.rsna.org
PURPOSE: To prospectively assess the oxygenation state of renal transplants and determine
the feasibility of using blood oxygen level–dependent (BOLD) magnetic resonance (MR) …