Cerebral blood flow and brain function in hypertension

M Fujishima, S Ibayashi, K Fujii, S Mori - Hypertension Research, 1995 - jstage.jst.go.jp
In mild hypertensive patients, regional cerebral blood flow, measured by positron emission
tomography, was reduced in the frontal cortex and basal ganglia compared with …

Nox4 as the major catalytic component of an endothelial NAD (P) H oxidase

…, T Iyama, YH Han, J Takada, M Wakisaka, S Ibayashi… - Circulation, 2004 - Am Heart Assoc
Background— Recent evidence has suggested that reactive oxygen species are important
signaling molecules in vascular cells and play a pivotal role in the development of vascular …

Incidence and risk factors for subtypes of cerebral infarction in a general population: the Hisayama study

…, N Shinohara, H Arima, K Tanaka, S Ibayashi… - Stroke, 2000 - Am Heart Assoc
Background and Purpose—We estimated the incidence of first-ever cerebral infarction in
regard to its subtypes and analyzed their risk factors separately in a community-based …

LDL cholesterol and the development of stroke subtypes and coronary heart disease in a general Japanese population: the Hisayama study

…, K Yonemoto, J Hata, M Kubo, Y Tanizaki, S Ibayashi… - Stroke, 2009 - Am Heart Assoc
Background and Purpose— Although the relation between serum LDL cholesterol level and
coronary heart disease (CHD) is well established, its relation with stroke subtypes is less …

Stroke in patients on maintenance hemodialysis: a 22-year single-center study

…, S Fujimi, Y Kumai, H Tsuchimochi, S Ibayashi… - American journal of …, 2005 - Elsevier
Background: Few studies have reported the detailed clinical features of stroke in patients
with end-stage renal disease. We examined the frequency of the subtypes, mechanism, and …

A nonsynonymous SNP in PRKCH (protein kinase C η) increases the risk of cerebral infarction

…, Y Ohnishi, S Saito, T Kitazono, S Ibayashi… - Nature …, 2007 - nature.com
Cerebral infarction is the most common type of stroke and often causes long-term disability.
To investigate the genetic contribution to cerebral infarction, we conducted a case-control …

Postischemic gene transfer of interleukin-10 protects against both focal and global brain ischemia

H Ooboshi, S Ibayashi, T Shichita, Y Kumai, J Takada… - Circulation, 2005 - Am Heart Assoc
Background— Gene therapy may be a promising approach for treatment of brain ischemia,
although the efficiency of postischemic gene therapy is not established. Our goal in this study …

Free radical scavenger, edaravone, in stroke with internal carotid artery occlusion

…, H Nakane, S Arihiro, Y Okada, S Ibayashi… - Journal of the …, 2004 - Elsevier
Background: Edaravone has potent free radical quenching and antioxidant actions. The agent
has been recently in commercial use for acute ischemic stroke patients. In this study, we …

[HTML][HTML] NAD (P) H oxidases in rat basilar arterial endothelial cells

…, M Wakisaka, T Kawahara, K Rokutan, S Ibayashi… - Stroke, 2005 - journals.lww.com
Background and Purpose—Reactive oxygen species (ROS) may play a critical role in the
regulation of vascular tone and development of vascular diseases, such as stroke. NAD (P) H …

Blood pressure control and recurrence of hypertensive brain hemorrhage

S Arakawa, Y Saku, S Ibayashi, T Nagao, M Fujishima - Stroke, 1998 - Am Heart Assoc
Background and Purpose—Recent studies have demonstrated that recurrence of hypertensive
brain hemorrhage (HBH) is not uncommon. However, risk factors for the recurrence of …