Genome-wide losses of DNA methylation have been regarded as a common epigenetic
event in malignancies and may play crucial roles in carcinogenesis. Limited information is …

Rabies is an almost invariably fatal disease that can present as classic furious rabies or
paralytic rabies. Recovery has been reported in only a few patients, most of whom were infected …

Introduction The efficacy of epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors
in EGFR mutation-positive non–small-cell lung cancer (NSCLC) patients necessitates …

BACKGROUND Published research on the clinicopathologic features of extraventricular
ependymal neoplasms of the cerebral hemispheres has been scant. METHODS Thirty‐two …

Whereas paralysis is the hallmark for paralytic rabies, the precise pathological basis of
paralysis is not known. It is unclear whether weakness results from involvement of anterior horn …

This study evaluated methylation patterns of long interspersed nuclear element-1 (LINE-1)
sequences from 17 loci in several cell types, including squamous cell cancer cell lines, …

Background The aim of our study is to describe the unusual clinical manifestations of smooth-muscle
tumors (SMTs) in patients with acquired immunodeficiency virus (AIDS) and to …

SHP-1 promoter hypermethylation has been studied in hematopoietic cells and observed
only in various types of lymphoma and leukemia. This study reports a contrasting situation in …

Context: Pituitary blastoma causing Cushing's syndrome in infancy is very rare, and its
molecular pathomechanism is not well understood. Objective: Our objective was to identify …

Despite the development of predictive biomarkers to shape treatment paradigms and outcomes,
de novo EGFR TKI resistance advanced non-small cell lung cancer (NSCLC) remains …