Intracellular calcium release is required for caspase‐3 and‐9 activation
L Tantral, K Malathi, S Kohyama… - Cell biochemistry …, 2004 - Wiley Online Library
Increase in intracellular Ca 2+ [Ca 2+ ]i regulates many biological functions including
apoptosis, but the protein(s) linking [Ca 2+ ]i and apoptosis are not completely understood. We …
apoptosis, but the protein(s) linking [Ca 2+ ]i and apoptosis are not completely understood. We …
The safety and efficacy of preoperative embolization of meningioma with N-butyl cyanoacrylate
…, Y Kakehi, N Uemiya, S Kohyama… - Interventional …, 2015 - journals.sagepub.com
Objective Preoperative embolization of meningioma is commonly performed; however,
there is no consensus on the best embolic material to reduce intraoperative blood loss and …
there is no consensus on the best embolic material to reduce intraoperative blood loss and …
Optimal first coil selection to avoid aneurysmal recanalization in endovascular intracranial aneurysmal coiling
H Neki, S Kohyama, T Otsuka, A Yonezawa… - Journal of …, 2018 - jnis.bmj.com
Background Aneurysmal recanalization is a problem with endovascular coiling and one of
its risk factors is the low volume embolization ratio (VER). The first coil VER (1st VER) is …
its risk factors is the low volume embolization ratio (VER). The first coil VER (1st VER) is …
Risk factors for coil protrusion into the parent artery and associated thrombo-embolic events following unruptured cerebral aneurysm embolization
…, Y Kakehi, N Uemiya, S Kohyama… - Interventional …, 2015 - journals.sagepub.com
Objective Advances in vascular reconstruction devices and coil technologies have made coil
embolization a popular and effective strategy for treatment of relatively wide-neck cerebral …
embolization a popular and effective strategy for treatment of relatively wide-neck cerebral …
Inositol 1, 4, 5‐trisphosphate receptor (type 1) phosphorylation and modulation by Cdc2
K Malathi, S Kohyama, M Ho… - Journal of cellular …, 2003 - Wiley Online Library
Calcium (Ca 2+ ) release from the endoplasmic reticulum (ER) controls numerous cellular
functions including proliferation, and is regulated in part by inositol 1,4,5‐trisphosphate …
functions including proliferation, and is regulated in part by inositol 1,4,5‐trisphosphate …
Altered expression of MicroRNA-15a and Kruppel-like factor 4 in cerebrospinal fluid and plasma after aneurysmal subarachnoid hemorrhage
…, H Nakajima, T Ikeda, R Takeda, H Neki, S Kohyama… - World Neurosurgery, 2017 - Elsevier
Background Cerebral vasospasm (CVS) is a major determinant of prognosis in patients with
subarachnoid hemorrhage (SAH). Alteration in the vascular phenotype contributes to …
subarachnoid hemorrhage (SAH). Alteration in the vascular phenotype contributes to …
Drip-and-ship thrombolytic therapy for acute ischemic stroke
I Deguchi, S Mizuno, S Kohyama, N Tanahashi… - Journal of Stroke and …, 2018 - Elsevier
Background Neuroendovascular therapy is a common treatment for patients with acute ischemic
stroke of the anterior circulation who fail to respond to recombinant tissue plasminogen …
stroke of the anterior circulation who fail to respond to recombinant tissue plasminogen …
Clinical features of neurogenic pulmonary edema in patients with subarachnoid hemorrhage
…, R Takeda, T Ikeda, Y Kikkawa, S Iihoshi, S Kohyama… - World Neurosurgery, 2020 - Elsevier
Objective Neurogenic pulmonary edema (NPE) is a clinical syndrome characterized by acute
onset after central nervous system injury. Here, we investigated the clinical features of NPE …
onset after central nervous system injury. Here, we investigated the clinical features of NPE …
Risk factors and prevention of guiding catheter-induced vasospasm in neuroendovascular treatment
…, H Neki, Y Kakehi, N Uemiya, S Kohyama… - Neurologia medico …, 2015 - jstage.jst.go.jp
Mechanically-induced vasospasm often occurs during guiding catheter insertion, occasionally
preventing catheter advancement to the desired location. Delicate manipulation would be …
preventing catheter advancement to the desired location. Delicate manipulation would be …
Clinical features of ruptured very small intracranial aneurysms (< 3 mm) in patients with subarachnoid hemorrhage
…, Y Take, A Teranishi, K Suzuki, S Kohyama… - World Neurosurgery, 2022 - Elsevier
Objective Although small unruptured aneurysms rarely rupture, many patients with subarachnoid
hemorrhage (SAH) have ruptured small, especially very small intracranial aneurysms (…
hemorrhage (SAH) have ruptured small, especially very small intracranial aneurysms (…