The glymphatic system is a glial-dependent waste clearance pathway in the brain, in place
of lymphatic vessels, dedicated to drain away soluble waste proteins and metabolic products. …

Metabolically, the brain is a highly active organ that relies almost exclusively on glucose as
its energy source. According to the astrocyte-to-neuron lactate shuttle hypothesis, glucose is …

Myelination by oligodendrocytes is a highly specialized process that relies on intimate
interactions between the axon and the oligodendrocytes. Astrocytes have an important part in …

The glymphatic system is a brainwide CSF transport system that uses the perivascular space
for fast inflow of CSF. Arterial pulsations are a major driver of glymphatic CSF inflow, and …

Purpose We propose a quantitative technique to assess solute uptake into the brain
parenchyma based on dynamic contrast‐enhanced MRI (DCE‐MRI). With this approach, a small …

The glymphatic system (GS) hypothesis states that advective driven cerebrospinal fluid (CSF)
influx from the perivascular spaces into the interstitial fluid space rapidly transport solutes …

Cisterna magna cannulation (CMc) is a straightforward procedure that enables direct
access to the cerebrospinal fluid (CSF) without operative damage to the skull or the brain …

Cerebral small vessel disease(s) (SVD) results from pathological changes of the small blood
vessels in the brain and is common in older people. The diagnostic features by which SVD …

Carbon dioxide (CO 2 ) is traditionally considered as metabolic waste, yet its regulation is
critical for brain function. It is well accepted that hypercapnia initiates vasodilation, but its effect …

… Sunil Koundal, # 1 Rena Elkin, # 2 Saad Nadeem, 3 Yuechuan Xue, 1 Stefan
Constantinou, 1 Simon Sanggaard, 1 Xiaodan Liu, 1 Brittany Monte, 1 Feng Xu, 4 William …