OBJECTIVE: The purpose of the study was to develop a standardized instrument, the
Behavior Rating Scale for Dementia, for rating psychopathology in patients with probable …

Background The validity of the clinical diagnosis of vascular dementia (VaD) remains
suboptimal. Objective To investigate clinicopathologic correlations in VaD. Methods We used the …

Studies of Asian populations generally have reported prevalence rates for dementia similar
to those of predominantly Caucasian populations, but relative prevalence rates of …

Background The Mini-Mental State Examination (MMSE) is the most widely used brief screening
measure of cognition, but it is not sensitive in detecting mild memory or other cognitive …

Objective: To determine the 1 H MR spectroscopic (MRS) findings and intergroup differences
among common dementias: Alzheimer disease (AD), vascular dementia (VaD), dementia …

Background Incidence rates of Alzheimer disease (AD) were higher in women than in men
in several recent European and Asian studies. Cohort studies in the United States, on the …

Background . — Although Alzheimer's disease (AD) is a progressive degenerative condition,
there is great intra- and inter-individual variability in rates of cognitive decline. Thus far, little …

Predisposition to sporadic Alzheimer's disease (SAD) involves interactions between a
person's unique combination of genetic variants and the environment. The molecular effect of …

Isovaleric acidemia (IVA) is an inborn error of leucine metabolism that can cause significant
morbidity and mortality. Since the implementation, in many states and countries, of newborn …

Objective: To examine frequencies and relationships of 5 common neuropathologic
abnormalities identified at autopsy with late-life cognitive impairment and dementia in 2 different …