User profiles for Susanne Wegener

Susanne Wegener

Neurology; University Hospital Zurich and University of Zurich
Verified email at usz.ch
Cited by 3286

Transient ischemic attacks before ischemic stroke: preconditioning the human brain? A multicenter magnetic resonance imaging study

S Wegener, B Gottschalk, V Jovanovic, R Knab… - Stroke, 2004 - Am Heart Assoc
Background and Purpose— We investigated whether transient ischemic attacks (TIAs) before
stroke can induce tolerance by raising the threshold of tissue vulnerability in the human …

[PDF][PDF] Neutrophils obstructing brain capillaries are a major cause of no-reflow in ischemic stroke

…, H Meister, A Luft, M Weller, B Weber, S Wegener - Cell reports, 2020 - cell.com
Despite successful clot retrieval in large vessel occlusion stroke, ∼50% of patients have an
unfavorable clinical outcome. The mechanisms underlying this functional reperfusion failure …

Aspirin versus anticoagulation in cervical artery dissection (TREAT-CAD): an open-label, randomised, non-inferiority trial

…, CH Nolte, H Christensen, S Wegener… - The Lancet …, 2021 - thelancet.com
Background Cervical artery dissection is a major cause of stroke in young people (aged <50
years). Historically, clinicians have preferred using oral anticoagulation with vitamin K …

[HTML][HTML] Ultrasound trapping and navigation of microrobots in the mouse brain vasculature

…, C Glück, J Droux, Y Ferry, C Frei, S Wegener… - Nature …, 2023 - nature.com
The intricate and delicate anatomy of the brain poses significant challenges for the treatment
of cerebrovascular and neurodegenerative diseases. Thus, precise local drug delivery in …

[HTML][HTML] Deep optoacoustic localization microangiography of ischemic stroke in mice

…, Z Chen, Q Zhou, B Weber, S Wegener… - Nature …, 2023 - nature.com
Super-resolution optoacoustic imaging of microvascular structures deep in mammalian tissues
has so far been impeded by strong absorption from densely-packed red blood cells. Here …

Heart–brain interactions in cardiac and brain diseases: why sex matters

…, V Treyer, RR Buechel, S Wegener… - European heart …, 2022 - academic.oup.com
Cardiovascular disease and brain disorders, such as depression and cognitive dysfunction,
are highly prevalent conditions and are among the leading causes limiting patient’s quality …

A generative probabilistic model and discriminative extensions for brain lesion segmentation—with application to tumor and stroke

…, E Alberts, P Gruber, S Wegener… - IEEE transactions on …, 2015 - ieeexplore.ieee.org
We introduce a generative probabilistic model for segmentation of brain lesions in multi-dimensional
images that generalizes the EM segmenter, a common approach for modelling …

[HTML][HTML] Improving cerebral blood flow after arterial recanalization: a novel therapeutic strategy in stroke

M El Amki, S Wegener - International journal of molecular sciences, 2017 - mdpi.com
Ischemic stroke is caused by a disruption in blood supply to a region of the brain. It induces
dysfunction of brain cells and networks, resulting in sudden neurological deficits. The cause …

No-reflow phenomenon in stroke patients: a systematic literature review and meta-analysis of clinical data

…, CC Kurmann, DJ Seiffge, S Wegener… - … Journal of Stroke, 2024 - journals.sagepub.com
Background: The no-reflow phenomenon refers to the absence of microvascular reperfusion
despite macrovascular reperfusion. Aim: The aim of this analysis was to summarize the …

Aetiology, secondary prevention strategies and outcomes of ischaemic stroke despite oral anticoagulant therapy in patients with atrial fibrillation

…, T Uphaus, K Gröschel, M Katan, S Wegener… - Journal of Neurology …, 2022 - jnnp.bmj.com
Objective To investigate the aetiology, subsequent preventive strategies and outcomes of
stroke despite anticoagulation in patients with atrial fibrillation (AF). Methods We analysed …