Background Moyamoya disease is an idiopathic vascular disorder of intracranial arteries. Its
susceptibility locus has been mapped to 17q25.3 in Japanese families, but the susceptibility …

Background and Purpose— About one half of those who develop adult-onset moyamoya
disease experience intracranial hemorrhage. Despite the extremely high frequency of …

Background and Purpose— The Middle Cerebral Artery Embolism Local Fibrinolytic
Intervention Trial (MELT) Japan was organized to determine the safety and clinical efficacy of …

Background—Oxidized LDL (Ox-LDL) seems to play key roles in atherogenesis. Lectinlike
Ox-LDL receptor-1 (LOX-1) is a recently identified cell-surface receptor for Ox-LDL. The …

Familial hypercholesterolemia (FH) is characterized by severe hypercholesterolemia and
premature coronary heart disease (CHD). The lower the plasma cholesterol level, the more …

✓ Between May, 1974, and March, 1991, 104 patients with moyamoya disease, all under 16
years old at the time of first surgery, underwent superficial temporal-to-middle cerebral …

Oxidized low density lipoprotein (Ox-LDL) induces apoptosis in vascular smooth muscle cells
(VSMCs), which may increase atherosclerotic plaque instability. In this study, we examined …

We studied the effects of ML-236B, a competitive inhibitor of 3-hydroxy-3-methylglutaryl
coenzyme A (HMG-CoA) reductase, on serum levels of lipoproteins and ubiquinone-10 in seven …

… TAKAHASHI,4 Hidenori ENDO,5 Kuniaki OGASAWARA,6 Susumu MIYAMOTO,7 Research
Committee on Moyamoya Disease (Spontaneous Occlusion of Circle of Willis) of the Ministry …

The objective of this study is to enhance the bone induction activity of basic fibroblast growth
factor (bFGF) for reconstruction of skull bone defects which has been clinically recognized …