[HTML][HTML] Genome-wide localization of the nuclear transport machinery couples transcriptional status and nuclear organization
The association of genes with the nuclear pore complex (NPC) and nuclear transport factors
has been implicated in transcriptional regulation. We therefore examined the association of …
has been implicated in transcriptional regulation. We therefore examined the association of …
[HTML][HTML] Functional specificity among ribosomal proteins regulates gene expression
Duplicated genes escape gene loss by conferring a dosage benefit or evolving diverged
functions. The yeast Saccharomyces cerevisiae contains many duplicated genes encoding …
functions. The yeast Saccharomyces cerevisiae contains many duplicated genes encoding …
Coupling and coordination in gene expression processes: a systems biology view
S Komili, PA Silver - Nature Reviews Genetics, 2008 - nature.com
Genome-scale analyses have allowed us to progress beyond studying gene expression at
the level of individual components of a given process by providing global information about …
the level of individual components of a given process by providing global information about …
[HTML][HTML] The genome-wide localization of Rsc9, a component of the RSC chromatin-remodeling complex, changes in response to stress
M Damelin, I Simon, TI Moy, B Wilson, S Komili… - Molecular cell, 2002 - cell.com
The cellular response to environmental changes includes widespread modifications in gene
expression. Here we report the identification and characterization of Rsc9, a member of the …
expression. Here we report the identification and characterization of Rsc9, a member of the …
Arginine methyltransferase affects interactions and recruitment of mRNA processing and export factors
…, F Bachand, AE McBride, S Komili… - Genes & …, 2004 - genesdev.cshlp.org
Hmt1 is the major type I arginine methyltransferase in the yeast Saccharomyces cerevisiae
and facilitates the nucleocytoplasmic transport of mRNA-binding proteins through their …
and facilitates the nucleocytoplasmic transport of mRNA-binding proteins through their …
eIF5A binds to translational machinery components and affects translation in yeast
CF Zanelli, ALC Maragno, APB Gregio, S Komili… - Biochemical and …, 2006 - Elsevier
The putative translation factor eIF5A is essential for cell viability and is highly conserved from
archebacteria to mammals. Although this protein was originally identified as a translation …
archebacteria to mammals. Although this protein was originally identified as a translation …
[PDF][PDF] Genomic association of the proteasome demonstrates overlapping gene regulatory activity with transcription factor substrates
The proteasome can regulate transcription through proteolytic processing of transcription
factors and via gene locus binding, but few targets of proteasomal regulation have been …
factors and via gene locus binding, but few targets of proteasomal regulation have been …
Iron-induced susceptibility effect at the globus pallidus causes underestimation of flow and volume on dynamic susceptibility contrast-enhanced MR perfusion images
…, RG Gonzalez, L Østergaard, S Komili… - American journal …, 2002 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Age-related iron accumulation in extrapyramidal nuclei
causes T2 shortening, which may result in decreased signal intensity in these areas on MR …
causes T2 shortening, which may result in decreased signal intensity in these areas on MR …
Genetic interaction screens advance in reverse
S Komili, FP Roth - Genes & development, 2007 - genesdev.cshlp.org
A genetic interaction is defined by the emergence of a surprising phenotype when two
genes are disrupted together. In 2004, Baetz et al.(2004) reported a new kind of large-scale …
genes are disrupted together. In 2004, Baetz et al.(2004) reported a new kind of large-scale …
[BOOK][B] Ribosomal heterogeneity and translational regulation in Saccharomyces cerevisiae
SSKL Komili - 2008 - search.proquest.com
RNA localization plays an important role in the establishment of cell polarity and in development.
During transport, localized mRNAs are translationally repressed, with translation only …
During transport, localized mRNAs are translationally repressed, with translation only …
