From 7% to 10% of all retinoblastomas and from 44% to 71% of familial retinoblastomas in
developed countries are diagnosed in the neonatal period, usually through pre- or post-natal …

Retinoblastoma is the most common intraocular malignancy. Its incidence has been reported
to be 1 case in from 15 000 to 18 000 live births, or approximately 12, 6, or 4 cases per 1 …

Purpose: To report our experience in superselective ophthalmic artery infusion of melphalan
(SOAIM) for intraocular retinoblastoma. Methods: From June 2008 to October 2010, 38 …

Background Ophthalmic artery chemosurgery [OAC, intra-arterial chemotherapy (IAC)] was
introduced in 2006 as treatment modality for intraocular retinoblastoma. The purpose of this …

BACKGROUND AND PURPOSE: Intralesional calcium deposition is considered a key element
for differentiating retinoblastoma from simulating lesions. Our aim was to assess whether …

Simple Summary Retinoblastoma is a rare cancer that develops in the retina of children.
Accurate differentiation between retinoblastoma and conditions that show similarities with …

Retinoblastoma is the most common primary intraocular malignancy in children. Two step
inactivation of RB1 (M1-M2) represents the key event in the pathogenesis of retinoblastoma …

It has been proposed that retinoblastoma is ‘caused’ by two sequential mutations affecting
the RB1 gene, but this is a rather outdated view of cancer aetiology that does not take into …

… 1666C>T in exon 17 of patient 704 and c.2212-1G>T in exon 22 of patient 762, t-test
demonstrated that the differences were statistically significant (Table 4). Suspected mosaicism of …

… Statistical analysis was conducted using the Student's t-test. … , but no significant correlation
was detected (statistical analysis was conducted using Student's t-test and χ 2 test). However, …