Curcumin has a long history of use as a traditional remedy and food in Asia. Many studies
have reported that curcumin has various beneficial properties, such as antioxidant, …

… Recently, we used fluorescence spectroscopy with thioflavin T (ThT) and electron
microscopy (EM) to examine the effects of wine-related polyphenols, myricetin (Myr), morin (Mor), …

The number of deaths from colorectal cancer in Japan continues to increase. Colorectal
cancer deaths exceeded 50,000 in 2016. In the 2019 edition, revision of all aspects of …

Background: No method for the clinical diagnosis of MM2-type sporadic Creutzfeldt-Jakob
disease (sCJD) has been established except for pathologic examination. Objective: To identify …

NK911 is a novel supramolecular nanocarrier designed for the enhanced delivery of
doxorubicin (DXR) and is one of the successful polymer micelle systems to exhibit an efficient …

Japanese mortality due to colorectal cancer is on the rise, surpassing 49,000 in 2015. Many
new treatment methods have been developed during recent decades. The Japanese …

… for patients with T stage clinically diagnosed as “invasion depth cSS/cA or deeper or cN-positive;”
postoperative radiotherapy is indicated for patients with T stage pathologically …

Colorectal cancer is a major cause of death in Japan, where it accounts for the largest number
of deaths from malignant neoplasms among women and the third largest number among …

… The statistical significance of the differences in neurotoxic activity between two administration
groups was calculated using the Student's t-test on the closed testing procedure. The …

This phase I study was designed to examine the maximum tolerated dose (MTD), the dose-limiting
toxicities (DLTs), the recommended dose (RD) for phase II, and the pharmacokinetics …