[HTML][HTML] microRNA-1/133a and microRNA-206/133b clusters: dysregulation and functional roles in human cancers

N Nohata, T Hanazawa, H Enokida, N Seki - Oncotarget, 2012 - ncbi.nlm.nih.gov
MicroRNAs (miRNAs) are endogenous short non-coding RNA molecules that regulate gene
expression by repressing translation or cleaving RNA transcripts in a sequence-specific …

Phoneme recognition using time-delay neural networks

A Waibel, T Hanazawa, G Hinton, K Shikano… - …, 2013 - taylorfrancis.com
In this paper we present a Time-Delay Neural Network (TDNN) approach to phoneme
recognition which is characterized by two important properties. 1) Using a 3 layer arrangement of …

Present situation of cedar pollinosis in Japan and its immune responses

…, H Yamamoto, S Yonekura, T Hanazawa - Allergology …, 2009 - Elsevier
… induction of allergen-specific effector T cells from naïve T cells. We examined the number of
… Natural killer T(NKT) cells represent a unique lymphocyte subpopulation and their activity is …

Oxidative stress reduces histone deacetylase 2 activity and enhances IL-8 gene expression: role of tyrosine nitration

K Ito, T Hanazawa, K Tomita, PJ Barnes… - … and biophysical research …, 2004 - Elsevier
Oxidative stress is a characteristic of chronic inflammatory diseases. The reactive oxygen
intermediate hydrogen peroxide (H 2 O 2 ) is an important signaling molecule that modulates …

MicroRNAs function as tumor suppressors or oncogenes: aberrant expression of microRNAs in head and neck squamous cell carcinoma

N Nohata, T Hanazawa, T Kinoshita, Y Okamoto… - Auris Nasus …, 2013 - Elsevier
MicroRNAs (miRNAs) are endogenous short non-coding RNA molecules that regulate gene
expression by repressing translation or cleaving RNA transcripts in a sequence-specific …

Increased nitrotyrosine in exhaled breath condensate of patients with asthma

T Hanazawa, SA Kharitonov… - American journal of …, 2000 - atsjournals.org
The reaction of nitric oxide (NO) and superoxide anions (O 2 − ) in the airway results in the
formation of peroxynitrite, a highly reactive oxidant species. Peroxynitrite reacts with tyrosine …

Warthin tumor of the parotid gland: diagnostic value of MR imaging with histopathologic correlation

M Ikeda, K Motoori, T Hanazawa… - American journal …, 2004 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: The purpose of our study was to describe the MR imaging
appearance of Warthin tumors multiple MR imaging techniques and to interpret the …

[HTML][HTML] miR-1 as a tumor suppressive microRNA targeting TAGLN2 in head and neck squamous cell carcinoma

N Nohata, Y Sone, T Hanazawa, M Fuse, N Kikkawa… - Oncotarget, 2011 - ncbi.nlm.nih.gov
Based on the microRNA (miRNA) expression signatures of hypopharyngeal and esophageal
squamous cell carcinoma, we found that miR-1 was significantly down-regulated in cancer …

Plectin promotes migration and invasion of cancer cells and is a novel prognostic marker for head and neck squamous cell carcinoma

…, K Matsushita, Y Tonoike, Y Kodera, T Hanazawa… - Journal of …, 2012 - Elsevier
… The  2 test and Student's t test were used to compare … from twelve matched samples of
tumor (T) and adjacent non-tumor … between (T) and (N) was assessed by Student's t-test for …

[HTML][HTML] Tumor suppressive microRNA-218 inhibits cancer cell migration and invasion through targeting laminin-332 in head and neck squamous cell carcinoma

T Kinoshita, T Hanazawa, N Nohata, N Kikkawa… - Oncotarget, 2012 - ncbi.nlm.nih.gov
Recent our microRNA (miRNA) expression signature revealed that expression of microRNA-218
(miR-218) was reduced in cancer tissues, suggesting a candidate of tumor suppressor …