… Engagement of PD-1 with clone 129 inhibited the proliferation and cytokine production of T
cells upon stimulation with anti-CD3 antibody and we changed its name from clone 129 to PD…

… PD-1 is expressed on CD4 − CD8 − double-negative αβ and γδ T cells in thymus and on
activated T cells, B cells, natural killer cells, natural killer T cells and myeloid cells in the …

… to switch off autoreactive T cells and induce peripheral tolerance, whereas those on parenchymal
cells prevent tissue destruction by suppressing effector T cells to maintain tolerance. In …

… Ig on the proliferation of murine T cells derived from wild-type and PD-1–deficient mice 21.
We first examined the proliferation of purified splenic T cells from wild-type and PD-1 −/ − …

… PD-1 is a receptor of the Ig superfamily that negatively regulates T cell antigen receptor …
less susceptible to the specific T cell antigen receptor-mediated lysis by cytotoxic T cells in vitro, …

Dilated cardiomyopathy is a severe pathology of the heart with poorly understood etiology.
Disruption of the gene encoding the negative immunoregulatory receptor PD-1 in BALB/c …

… −/− splenic T cells differentiated into either type 1 or type 2 helper T cells (T H 1 and T H 2) …
Thus, we investigated the activation of T cells in the pulmonary lymph nodes 9 d after N. …

PD-1 is an immunoreceptor that belongs to the immunoglobulin (Ig) superfamily and contains
two tyrosine residues in the cytoplasmic region. Studies on PD-1-deficient mice have …

Programmed death 1 (PD-1)–deficient mice develop a variety of autoimmune-like diseases,
which suggests that this immunoinhibitory receptor plays an important role in tolerance. We …

… PD‐1 expression on T cells was analyzed in blood samples from 10 patients who had … T
cells had significantly higher PD‐1 expression levels in the peripheral blood. Tumor‐infiltrating T …