More than two decades have passed since genetically modified HIV was used for gene
delivery. Through continuous improvements these early marker gene-carrying HIVs have …

The main objective of this review was to assess the role of dairy cattle and their products in
human infections with Shiga toxin-producing Escherichia coli (STEC). A large number of …

We describe a group of alloys that exhibit “super” properties, such as ultralow elastic modulus,
ultrahigh strength, super elasticity, and super plasticity, at room temperature and that …

… In patients who underwent Occ-C/T or C1–C2 posterior fusion, we used C1–C2 TAS as
anchors to C2 from July 1998 through October 2005, and a C2 pedicle screw (PS) from …

A new compound has been found, (S)-9-(3-hydroxy-2-phosphonyl-methoxypropyl)adenine ((S)-HPMPA),
that has potent and selective activity against a broad spectrum of DNA viruses, …

Duchenne muscular dystrophy (DMD) is a severe muscle-degenerative disease caused by
a mutation in the dystrophin gene. Genetic correction of patient-derived induced pluripotent …

… Erik De Clercq’, Takashi Sakuma ‘. Masanori Baba’, Rudi Pauwels’, Jan Balzarini’, Ivan
Rosenberg’ and … thymine (T)] have been evaluated for their antiviral properties. PMEDAP, …

Genome engineering using programmable nucleases enables homologous recombination (HR)-mediated
gene knock-in. However, the labour used to construct targeting vectors …

Mechanisms underlying human germ cell development are unclear, partly due to difficulties
in studying human embryos and lack of suitable experimental systems. Here, we show that …

When mature adipocytes are subjected to an in vitro dedifferentiation strategy referred to as
ceiling culture, these mature adipocytes can revert to a more primitive phenotype and gain …