User profiles for T. Sursal

Tolga Sursal

Neurosurgeon, Sentara Martha Jefferson Hospital
Verified email at sentara.com
Cited by 4682

Circulating mitochondrial DAMPs cause inflammatory responses to injury

Q Zhang, M Raoof, Y Chen, Y Sumi, T Sursal, W Junger… - Nature, 2010 - nature.com
… Study data were assessed for statistical significance using Student’s (unpaired) t-test or
analysis of variance where appropriate using a SigmaStat program with post hoc tests chosen by …

[HTML][HTML] Mitochondrial DAMPs increase endothelial permeability through neutrophil dependent and independent pathways

S Sun, T Sursal, Y Adibnia, C Zhao, Y Zheng, H Li… - PloS one, 2013 - journals.plos.org
Trauma and sepsis can cause acute lung injury (ALI) and Acute Respiratory Distress Syndrome
(ARDS) in part by triggering neutrophil (PMN)-mediated increases in endothelial cell (EC…

Molecular stratification of medulloblastoma: clinical outcomes and therapeutic interventions

T Sursal, JS Ronecker, AJ Dicpinigaitis… - Anticancer …, 2022 - ar.iiarjournals.org
… This approach was a combination of the following techniques: t-Distributed Stochastic
Neighbor Embedding (t-SNE), a dimension reduction technique, and density-based clustering of …

Cerebral venous thrombosis in COVID-19: a New York metropolitan cohort study

…, JF Dominguez, T Sursal… - American journal …, 2021 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2)
infection is associated with hypercoagulability. We sought to evaluate the …

Mitochondrial damage associated molecular patterns from femoral reamings activate neutrophils through formyl peptide receptors and P44/42 MAP kinase

CJ Hauser, T Sursal, EK Rodriguez… - … of orthopaedic trauma, 2010 - journals.lww.com
Methods: Femur fracture reamings (FFx) from 10 patients were spun to remove bone particulates.
Supernatants were assayed for mitochondrial DNA. Mitochondria were isolated from …

Potential for treatment of glioblastoma: new aspects of superparamagnetic iron oxide nanoparticles

D Marekova, K Turnovcova, TH Sursal… - Anticancer …, 2020 - ar.iiarjournals.org
Glioblastoma (GB) is a highly aggressive and infiltrative brain tumor characterized by poor
outcomes and a high rate of recurrence despite maximal safe resection, chemotherapy, and …

Plasma bacterial and mitochondrial DNA distinguish bacterial sepsis from sterile systemic inflammatory response syndrome and quantify inflammatory tissue injury in …

T Sursal, DJ Stearns-Kurosawa, K Itagaki, SY Oh… - Shock, 2013 - journals.lww.com
… Data were analyzed for differences between baboon groups using Student t test, assuming
equal variance. To identify the relationships of plasma mtDNA and bDNA to organ function in …

Effect of helicopter transportation of acute ischemic stroke patients on mortality and functional outcomes: a systematic review and meta-analysis

…, SK Konar, L Ramos-Gomez, F Al-Mufti, T Sursal… - Air Medical Journal, 2022 - Elsevier
Objective The “time is brain” concept denotes the importance of the expedited transfer of
patients to stroke care centers. Helicopter emergency medical services (HEMS) can reduce the …

Endovascular thrombectomy for treatment of acute ischemic stroke during pregnancy and the early postpartum period

AJ Dicpinigaitis, T Sursal, CA Morse, C Briskin… - Stroke, 2021 - Am Heart Assoc
… Estimated marginal means for continuous baseline parameters were computed by t test …
Following propensity score matching, clinical end points were compared using χ 2 analysis and t

Laterality and location influence catamenial seizure expression in women with partial epilepsy

M Quigg, SD Smithson, KM Fowler, T Sursal… - Neurology, 2009 - AAN Enterprises
Objective: The temporal distribution of seizures in women with localization-related epilepsy
occurs periodically according to a model “clock” with the peak phase of occurrence …