Esthesioneuroblastoma
TJ Ow, D Bell, ME Kupferman… - Neurosurgery …, 2013 - neurosurgery.theclinics.com
Esthesioneuroblastoma (ENB) was first described by Berger and Richard in 1924. 1 It has
been characterized as a rare malignant neoplasm of the sinonasal cavity that arises in the …
been characterized as a rare malignant neoplasm of the sinonasal cavity that arises in the …
Mechanisms of invasion in head and neck cancer
L Jimenez, SK Jayakar, TJ Ow… - Archives of pathology …, 2015 - meridian.allenpress.com
Context The highly invasive properties demonstrated by head and neck squamous cell
carcinoma (HNSCC) are often associated with locoregional recurrence and lymph node …
carcinoma (HNSCC) are often associated with locoregional recurrence and lymph node …
TP53 Disruptive Mutations Lead to Head and Neck Cancer Treatment Failure through Inhibition of Radiation-Induced Senescence
HD Skinner, VC Sandulache, TJ Ow, RE Meyn… - Clinical cancer …, 2012 - AACR
Purpose: Mortality of patients with head and neck squamous cell carcinoma (HNSCC) is
primarily driven by tumor cell radioresistance leading to locoregional recurrence (LRR). In this …
primarily driven by tumor cell radioresistance leading to locoregional recurrence (LRR). In this …
Assembly and initial characterization of a panel of 85 genomically validated cell lines from diverse head and neck tumor sites
…, YC Henderson, GL Clayman, EM Sturgis, TJ Ow… - Clinical cancer …, 2011 - AACR
Purpose: Human cell lines are useful for studying cancer biology and preclinically modeling
cancer therapy, but can be misidentified and cross-contamination is unfortunately common. …
cancer therapy, but can be misidentified and cross-contamination is unfortunately common. …
Evolutionary Action Score of TP53 Identifies High-Risk Mutations Associated with Decreased Survival and Increased Distant Metastases in Head and Neck Cancer
DM Neskey, AA Osman, TJ Ow, P Katsonis… - Cancer research, 2015 - AACR
TP53 is the most frequently altered gene in head and neck squamous cell carcinoma, with
mutations occurring in over two-thirds of cases, but the prognostic significance of these …
mutations occurring in over two-thirds of cases, but the prognostic significance of these …
Glucose, not glutamine, is the dominant energy source required for proliferation and survival of head and neck squamous carcinoma cells
VC Sandulache, TJ Ow, CR Pickering, MJ Frederick… - Cancer, 2011 - Wiley Online Library
BACKGROUND: Tumor metabolism is an essential contributor to disease progression and
response to treatment. An understanding of the metabolic phenotype of head and neck …
response to treatment. An understanding of the metabolic phenotype of head and neck …
Proteomic analysis of oral cavity squamous cell carcinoma specimens identifies patient outcome–associated proteins
…, Y Wang, NF Schlecht, TJ Ow… - … of Pathology and …, 2015 - meridian.allenpress.com
Context Global proteomic analysis of oral cavity squamous cell carcinoma was performed to
identify changes that reflect patient outcomes. Objectives To identify differentially expressed …
identify changes that reflect patient outcomes. Objectives To identify differentially expressed …
Prognostic utility of Hyams histological grading and Kadish-Morita staging systems for esthesioneuroblastoma outcomes
D Bell, R Saade, D Roberts, TJ Ow, M Kupferman… - Head and neck …, 2015 - Springer
Esthesioneuroblastoma (ENB) is derived from the specialized olfactory neuroepithelium.
Hyams grading and Kadish staging have been used to prognosticate and to guide treatment …
Hyams grading and Kadish staging have been used to prognosticate and to guide treatment …
Disruptive TP53 Mutation Is Associated with Aggressive Disease Characteristics in an Orthotopic Murine Model of Oral Tongue Cancer
D Sano, TX Xie, TJ Ow, M Zhao, CR Pickering… - Clinical cancer …, 2011 - AACR
… Immunostained slides were reviewed by 2 investigators (VC Sandulache and TJ Ow)
blinded to cell line and p53 status. Slides were scored for the presence of stained tumor cells, …
blinded to cell line and p53 status. Slides were scored for the presence of stained tumor cells, …
Optimization of long‐term outcomes for patients with esthesioneuroblastoma
TJ Ow, EY Hanna, DB Roberts, NB Levine… - Head & …, 2014 - Wiley Online Library
Background Esthesioneuroblastoma is a rare cancer of the anterior cranial base that arises
in the region of the olfactory rootlets. The purpose of this study was to review the long‐term …
in the region of the olfactory rootlets. The purpose of this study was to review the long‐term …
