User profiles for T.M. Gates

Thomas Gates

Ingham Institute for Applied Medical Research
Verified email at health.nsw.gov.au
Cited by 690

[HTML][HTML] The chronicity of HIV infection should drive the research strategy of NeuroHIV treatment studies: a critical review

TM Gates, LA Cysique - CNS drugs, 2016 - Springer
HIV infection has become a chronic illness when successfully treated with combined antiretroviral
therapy (cART). The long-term health prognosis of aging with controlled HIV infection …

Maraviroc-intensified combined antiretroviral therapy improves cognition in virally suppressed HIV-associated neurocognitive disorder

TM Gates, LA Cysique, KJ Siefried, J Chaganti… - Aids, 2016 - journals.lww.com
Objective: To investigate whether intensification of combined antiretroviral therapy (cART) with
the CC chemokine receptor type 5 (CCR5) entry inhibitor maraviroc leads to improvement …

HIV-associated neurocognitive disorder in Australia: a case of a high-functioning and optimally treated cohort and implications for international neuroHIV research

…, RK Heaton, J Kamminga, T Lane, TM Gates… - Journal of …, 2014 - Springer
The Australian HIV-infected (HIV+) population is largely comprised of high-functioning men
who have sex with men (MSM). Like other English-speaking countries, Australia mostly relies …

Elevation of cell-associated HIV-1 transcripts in CSF CD4+ T cells, despite effective antiretroviral therapy, is linked to brain injury

K Suzuki, J Zaunders, TM Gates… - Proceedings of the …, 2022 - National Acad Sciences
Antiretroviral therapy (ART) can attain prolonged undetectable HIV-1 in plasma and
cerebrospinal fluid (CSF), but brain injury remains prevalent in people living with HIV-1 infection (…

[HTML][HTML] Socioeconomic factors explain suboptimal adherence to antiretroviral therapy among HIV-infected Australian adults with viral suppression

KJ Siefried, L Mao, S Kerr, LA Cysique, TM Gates… - PLoS …, 2017 - journals.plos.org
… Thomas M Gates has no relevant interests to declare. John McAllister has no relevant …
Cysique LA, Heaton RK, Kamminga J, Lane T, Gates TM, Moore DM, et al. HIV-associated …

Functional connectivity in virally suppressed patients with HIV-associated neurocognitive disorder: a resting-state analysis

JR Chaganti, A Heinecke, TM Gates… - American Journal …, 2017 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: HIV-associated neurocognitive disorder still occurs despite
virally suppressive combination antiretroviral therapy. In the pre-combination antiretroviral …

Atrophic brain signatures of mild forms of neurocognitive impairment in virally suppressed HIV infection

MJ Nichols, TM Gates, JR Soares, KJ Moffat, CD Rae… - Aids, 2019 - journals.lww.com
Objective: There is a lack of evidence for the neurobiological underpinning of asymptomatic
neurocognitive impairment (ANI) and mild neurocognitive disorders (MNDs) in virally …

[HTML][HTML] Meaningful cognitive decline is uncommon in virally suppressed HIV, but sustained impairment, subtle decline and abnormal cognitive aging are not

HL Aung, KJ Siefried, TM Gates, BJ Brew, L Mao… - …, 2023 - thelancet.com
Background High antiretroviral therapy (ART) coverage and viral suppression among
people with HIV (PWH) in Australia provide a unique context to study individual cognitive …

Imaging correlates of the blood–brain barrier disruption in HIV-associated neurocognitive disorder and therapeutic implications

J Chaganti, K Marripudi, LP Staub, CD Rae, TM Gates… - Aids, 2019 - journals.lww.com
Objective: HIV-associated neurocognitive disorders (HANDs) in the context of suppressive
combination antiretroviral therapy (cART) still occur. We explored the role of blood–brain …

How all-type dementia risk factors and modifiable risk interventions may be relevant to the first-generation aging with HIV infection?

HL Aung, S Kootar, TM Gates, BJ Brew… - European Geriatric …, 2019 - Springer
Purpose The purpose of this review is to provide an overview of established risk factors for
all-type dementia and results of interventions on dementia modifiable risk factors, all with …