User profiles for T.M. Pearce

Thomas Pearce

Anatomic Pathology Resident, University of Pittsburgh Medical Center
Verified email at upmc.edu
Cited by 622

Microtechnology: meet neurobiology

TM Pearce, JC Williams - Lab on a Chip, 2007 - pubs.rsc.org
The field of neuroscience has always been attractive to engineers. Neurons and their
connections, like tiny circuit elements, process and transmit information in a dramatic way that is …

The spectrum of rare central nervous system (CNS) tumors with EWSR1‐non‐ETS fusions: experience from three pediatric institutions with review of the literature

…, M Santi, S Ranganathan, TM Pearce… - Brain …, 2021 - Wiley Online Library
The group of CNS mesenchymal (non‐meningothelial) and primary glial/neuronal tumors in
association with EWSR1‐non‐ETS rearrangements comprises a growing spectrum of …

Ecchordosis Physaliphora: Does It Even Exist?

…, P Gardner, TM Pearce… - American Journal …, 2023 - Am Soc Neuroradiology
The term ecchordosis physaliphora (EP) has been used historically to describe a benign
notochordal remnant with no growth potential, most commonly occuring in the central clivus. …

An externally driven magnetic microstirrer

GA Mensing, TM Pearce… - … Transactions of the …, 2004 - royalsocietypublishing.org
In this paper, an inexpensive, easy–to–fabricate active magnetic mixer is presented. This
mixer functions on top of a common magnetic stir plate and is capable of mixing two streams, …

Lymphatic endothelial-like cells promote glioblastoma stem cell growth through cytokine-driven cholesterol metabolism

L Zhao, Z Qiu, Z Yang, L Xu, TM Pearce, Q Wu, K Yang… - Nature Cancer, 2024 - nature.com
Glioblastoma is the most lethal primary brain tumor with glioblastoma stem cells (GSCs)
atop a cellular hierarchy. GSCs often reside in a perivascular niche, where they receive …

Multilayer PDMS microfluidic chamber for controlling brain slice microenvironment

AJ Blake, TM Pearce, NS Rao, SM Johnson… - Lab on a Chip, 2007 - pubs.rsc.org
A novel three-layer microfluidic polydimethylsiloxane (PDMS) device was constructed with
two fluid chambers that holds a brain slice in place with microposts while maintaining laminar …

Strategy-dependent encoding of planned arm movements in the dorsal premotor cortex

TM Pearce, DW Moran - Science, 2012 - science.org
The kinematic strategy encoded in motor cortical areas for classic straight-line reaching is
remarkably simple and consistent across subjects, despite the complicated musculoskeletal …

Integrated microelectrode array and microfluidics for temperature clamp of sensory neurons in culture

TM Pearce, JA Wilson, SG Oakes, SY Chiu… - Lab on a Chip, 2005 - pubs.rsc.org
A device for cell culture is presented that combines MEMS technology and liquid-phase
photolithography to create a microfluidic chip that influences and records electrical cellular …

[HTML][HTML] Homozygous deletion of CDKN2A by fluorescence in situ hybridization is prognostic in grade 4, but not grade 2 or 3, IDH-mutant astrocytomas

DF Marker, TM Pearce - Acta Neuropathologica Communications, 2020 - Springer
IDH-mutant astrocytomas have a more indolent natural history and better prognosis than
their IDH-wild type counterparts, but are still graded according to schemes developed prior to …

Intracranial myxoid mesenchymal tumor with rare EWSR1-CREM translocation

MD White, MM McDowell, TM Pearce… - Pediatric …, 2019 - karger.com
Translocations between EWSR1 and members of the CREB family of transcription factors (CREB1,
ATF1, and CREM) are rare genetic findings occurring in various sarcomas. Of these, …