The role of metallobiology and amyloid‐β peptides in Alzheimer's disease
The role of metallobiology and amyloid╒β peptides in Alzheimer╎s disease Page 1
Introduction: metals in biology In eukaryotes, the most abundant biochemically functional metals …
Introduction: metals in biology In eukaryotes, the most abundant biochemically functional metals …
Oxygen radical inhibition of nitric oxide-dependent vascular function in sickle cell disease
…, TM Ryan, B Adler, TM Townes… - Proceedings of the …, 2001 - National Acad Sciences
Plasma xanthine oxidase (XO) activity was defined as a source of enhanced vascular
superoxide (O \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \…
superoxide (O \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \…
Knockout-transgenic mouse model of sickle cell disease
TM Ryan, DJ Ciavatta, TM Townes - Science, 1997 - science.org
When transgenic mice that expressed human sickle hemoglobin were mated with mice
having knockout mutations of the mouse α- and β-globin genes, animals were produced that …
having knockout mutations of the mouse α- and β-globin genes, animals were produced that …
[HTML][HTML] Metalloproteomics: principles, challenges and applications to neurodegeneration
Trace elements are required for a variety of normal biological functions. As our understanding
of neurodegenerative disease advances we are identifying a number of metalloenzymes …
of neurodegenerative disease advances we are identifying a number of metalloenzymes …
Correction of sickle cell disease by homologous recombination in embryonic stem cells
…, CW Sun, TM Ryan, KM Pawlik, J Ren, TM Townes - Blood, 2006 - ashpublications.org
Previous studies have demonstrated that sickle cell disease (SCD) can be corrected in
mouse models by transduction of hematopoietic stem cells with lentiviral vectors containing …
mouse models by transduction of hematopoietic stem cells with lentiviral vectors containing …
The primate semicircular canal system and locomotion
…, T Garland Jr, G Krovitz, TM Ryan… - Proceedings of the …, 2007 - National Acad Sciences
The semicircular canal system of vertebrates helps coordinate body movements, including
stabilization of gaze during locomotion. Quantitative phylogenetically informed analysis of the …
stabilization of gaze during locomotion. Quantitative phylogenetically informed analysis of the …
The semicircular canal system and locomotion: the case of extinct lemuroids and lorisoids
Paleontologists reconstruct the locomotor and postural behavior of extinct species by analogy
with living forms and biomechanical analyses. In rare cases, behavioral evidence such as …
with living forms and biomechanical analyses. In rare cases, behavioral evidence such as …
[HTML][HTML] Utility of an improved model of amyloid-beta (Aβ1-42) toxicity in Caenorhabditis elegansfor drug screening for Alzheimer's disease
Background The definitive indicator of Alzheimer’s disease (AD) pathology is the profuse
accumulation of amyloid-ß (Aß) within the brain. Various in vitro and cell-based models have …
accumulation of amyloid-ß (Aß) within the brain. Various in vitro and cell-based models have …
Quantification and visualization of anisotropy in trabecular bone
RA Ketcham, TM Ryan - Journal of microscopy, 2004 - Wiley Online Library
A number of methods for measuring anisotropy in trabecular bone using high‐resolution X‐ray
computed tomography exist, which give different answers but have not been compared in …
computed tomography exist, which give different answers but have not been compared in …
Correction of a mouse model of sickle cell disease: lentiviral/antisickling β-globin gene transduction of unmobilized, purified hematopoietic stem cells
DN Levasseur, TM Ryan, KM Pawlik, TM Townes - Blood, 2003 - ashpublications.org
Although sickle cell anemia was the first hereditary disease to be understood at the
molecular level, there is still no adequate long-term treatment. Allogeneic bone marrow …
molecular level, there is still no adequate long-term treatment. Allogeneic bone marrow …