The COVID-19 vaccine development landscape
Profile of vaccine developers. Of the confirmed active vaccine candidates, 56 (72%) are being
developed by private/industry developers, with the remaining 22 (28%) of projects being …
developed by private/industry developers, with the remaining 22 (28%) of projects being …
[HTML][HTML] Covid-19 vaccines production and societal immunization under the serendipity-mindsponge-3D knowledge management theory and conceptual framework
Since the outbreak of the Coronavirus disease 2019 (Covid-19), tremendous efforts have
been made by scientists, health professionals, business people, politicians, and laypeople …
been made by scientists, health professionals, business people, politicians, and laypeople …
Evolution of the COVID-19 vaccine development landscape
TT Le, JP Cramer, R Chen, S Mayhew - Nat Rev Drug Discov, 2020 - nature.com
NEWS & ANALYSIS milder disease and are less likely to affect asymptomatic infection. In
addition, use of asymptomatic SARS-CoV-2 infection as an end point may be operationally …
addition, use of asymptomatic SARS-CoV-2 infection as an end point may be operationally …
[HTML][HTML] Prevalence and attributable health burden of chronic respiratory diseases, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017
…, S Lasrado, P Lauriola, C La Vecchia, TT Le… - The Lancet …, 2020 - thelancet.com
Background Previous attempts to characterise the burden of chronic respiratory diseases
have focused only on specific disease conditions, such as chronic obstructive pulmonary …
have focused only on specific disease conditions, such as chronic obstructive pulmonary …
Developments in construction-scale additive manufacturing processes
Additive manufacturing in construction is beginning to move from an architect's modelling
tool to delivering full-scale architectural components and elements of buildings such as walls …
tool to delivering full-scale architectural components and elements of buildings such as walls …
Mix design and fresh properties for high-performance printing concrete
This paper presents the experimental results concerning the mix design and fresh properties
of a high-performance fibre-reinforced fine-aggregate concrete for printing concrete. This …
of a high-performance fibre-reinforced fine-aggregate concrete for printing concrete. This …
Hardened properties of high-performance printing concrete
This paper presents the hardened properties of a high-performance fibre-reinforced fine-aggregate
concrete extruded through a 9mm diameter nozzle to build layer-by-layer structural …
concrete extruded through a 9mm diameter nozzle to build layer-by-layer structural …
The human centromeric survival motor neuron gene (SMN2) rescues embryonic lethality in Smn–/– mice and results in a mouse with spinal muscular atrophy
…, DW Parsons, C Andreassi, TT Le… - Human molecular …, 2000 - academic.oup.com
Proximal spinal muscular atrophy (SMA) is a common motor neuron disease in humans and
in its most severe form causes death by the age of 2 years. It is caused by defects in the …
in its most severe form causes death by the age of 2 years. It is caused by defects in the …
RETRACTED ARTICLE: Rescue of the spinal muscular atrophy phenotype in a mouse model by early postnatal delivery of SMN
Spinal muscular atrophy (SMA), the most common autosomal recessive neurodegenerative
disease affecting children, results in impaired motor neuron function 1 . Despite knowledge …
disease affecting children, results in impaired motor neuron function 1 . Despite knowledge …
The survival motor neuron protein in spinal muscular atrophy
DD Coovert, TT Le, PE McAndrew… - Human molecular …, 1997 - academic.oup.com
The 38 kDa survival motor neuron (SMN) protein is encoded by two ubiquitously expressed
genes: telomeric SMN (SMN T ) and centromeric SMN (SMN C ). Mutations in SMN T , but …
genes: telomeric SMN (SMN T ) and centromeric SMN (SMN C ). Mutations in SMN T , but …
