User profiles for T.Y. Tan

TY Tan

- Verified email at duke.edu - Cited by 10328

Thean Yen Tan

- Verified email at singhealth.com.sg - Cited by 8445

Tiong Yang Tan

- Verified email at vcgs.org.au - Cited by 8376

Epidemiologic features and clinical course of patients infected with SARS-CoV-2 in Singapore

…, SK Lau, DE Anderson, KS Chan, TY Tan, TY Ng… - Jama, 2020 - jamanetwork.com
Importance Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in
Wuhan, China, in December 2019 and has spread globally with sustained human-to-human …

[HTML][HTML] COVID-19 and the risk to health care workers: a case report

…, JL Shan Quah, WJ Loh, YJ Wong, TY Tan… - Annals of internal …, 2020 - acpjournals.org
Background: Little is known about the effectiveness of personal protective equipment for
health care workers who take care of patients infected with the novel coronavirus (SARS-CoV-2) …

Mutations in ADAR1 cause Aicardi-Goutières syndrome associated with a type I interferon signature

…, F Rozenberg, JL Schmidt, K Steindl, TY Tan… - Nature …, 2012 - nature.com
Adenosine deaminases acting on RNA (ADARs) catalyze the hydrolytic deamination of
adenosine to inosine in double-stranded RNA (dsRNA) and thereby potentially alter the …

Mutations involved in Aicardi-Goutieres syndrome implicate SAMHD1 as regulator of the innate immune response

…, SA Shalev, DM Soler, M Shinawi, R Spiegel, TY Tan… - Nature …, 2009 - nature.com
Aicardi-Goutières syndrome is a mendelian mimic of congenital infection and also shows
overlap with systemic lupus erythematosus at both a clinical and biochemical level. The recent …

Point defects, diffusion processes, and swirl defect formation in silicon

TY Tan, U Gösele - Applied Physics A, 1985 - Springer
The paper consists of three parts. In the first part we review the basic experimental and
theoretical results which shaped our present knowledge on point defects and diffusion processes …

Characterization of human disease phenotypes associated with mutations in TREX1, RNASEH2A, RNASEH2B, RNASEH2C, SAMHD1, ADAR, and IFIH1

…, KJ Swoboda, M Suri, U Tacke, TY Tan… - American journal of …, 2015 - Wiley Online Library
Aicardi–Goutières syndrome is an inflammatory disease occurring due to mutations in any
of TREX1, RNASEH2A, RNASEH2B, RNASEH2C, SAMHD1, ADAR or IFIH1. We report on …

[HTML][HTML] Meta-analysis of the diagnostic and clinical utility of genome and exome sequencing and chromosomal microarray in children with suspected genetic …

MM Clark, Z Stark, L Farnaes, TY Tan, SM White… - NPJ genomic …, 2018 - nature.com
Genetic diseases are leading causes of childhood mortality. Whole-genome sequencing (WGS)
and whole-exome sequencing (WES) are relatively new methods for diagnosing genetic …

Intrinsic gettering by oxide precipitate induced dislocations in Czochralski Si

TY Tan, EE Gardner, WK Tice - Applied Physics Letters, 1977 - pubs.aip.org
The presence of oxygen in Czochralski Si, either in solution or in precipitated forms, is known
to have a materials hardening effect. 1-3 This effect can enhance device leakage limited …

[PDF][PDF] Clinical and molecular phenotype of Aicardi-Goutieres syndrome

…, R Spiegel, JBP Stephenson, U Tacke, TY Tan… - The American Journal of …, 2007 - cell.com
Aicardi-Goutières syndrome (AGS) is a genetic encephalopathy whose clinical features mimic
those of acquired in utero viral infection. AGS exhibits locus heterogeneity, with mutations …

Silicon nanowhiskers grown on< 111> Si substrates by molecular-beam epitaxy

…, G Gerth, FM Kolb, L Long, U Gösele, TY Tan - Applied Physics …, 2004 - pubs.aip.org
Silicon nanowhiskers in the diameter range of 70 to 200 nm were grown on <111>-oriented
silicon substrates by molecular-beam epitaxy. Assuming the so-called “vapor–liquid–solid” (…