User profiles for Takayuki Obata

Takayuki Obata

Group Leader of Applied MRI Research, National Institutes for Quantum Science and …
Verified email at qst.go.jp
Cited by 5609

Discrepancies between BOLD and flow dynamics in primary and supplementary motor areas: application of the balloon model to the interpretation of BOLD transients

T Obata, TT Liu, KL Miller, WM Luh, EC Wong… - NeuroImage, 2004 - Elsevier
The blood-oxygen-level-dependent (BOLD) signal measured in the brain with functional
magnetic resonance imaging (fMRI) during an activation experiment often exhibits pronounced …

Negative Correlation between Brain Glutathione Level and Negative Symptoms in Schizophrenia: A 3T 1H-MRS Study

D Matsuzawa, T Obata, Y Shirayama, H Nonaka… - PloS one, 2008 - journals.plos.org
Background Glutathione (GSH), a major intracellular antioxidant, plays a role in NMDA
receptor-mediated neurotransmission, which is involved in the pathophysiology of schizophrenia. …

Age-related degeneration of corpus callosum measured with diffusion tensor imaging

M Ota, T Obata, Y Akine, H Ito, H Ikehira, T Asada… - Neuroimage, 2006 - Elsevier
The corpus callosum is the major commissure connecting the cerebral hemispheres, and
there is evidence of its change with aging. The sub-regions of the corpus callosum (genu, …

Spin‐locking versus chemical exchange saturation transfer MRI for investigating chemical exchange process between water and labile metabolite protons

T Jin, J Autio, T Obata, SG Kim - Magnetic resonance in …, 2011 - Wiley Online Library
Chemical exchange saturation transfer (CEST) and spin‐locking (SL) experiments were
both able to probe the exchange process between protons of nonequivalent chemical …

Nonlinear temporal dynamics of the cerebral blood flow response

…, WM Luh, TT Liu, A Martinez, T Obata… - Human brain …, 2001 - Wiley Online Library
The linearity of the cerebral perfusion response relative to stimulus duration is an important
consideration in the characterization of the relationship between regional cerebral blood flow …

Results of the first prospective study of carbon ion radiotherapy for hepatocellular carcinoma with liver cirrhosis

…, S Yamada, S Kandatsu, K Yoshikawa, T Obata… - International Journal of …, 2004 - Elsevier
PURPOSE: To evaluate the toxicity and antitumor effect of carbon ion radiotherapy for
hepatocellular carcinoma within a Phase I-II trial. METHODS AND MATERIALS: Between June …

Classification of intervertebral disk degeneration with axial T2 mapping

…, C Boesch, T Watanabe, T Obata… - American Journal of …, 2007 - Am Roentgen Ray Soc
OBJECTIVE. The aim of this study was to establish an MRI classification system for intervertebral
disks using axial T2 mapping, with a special focus on evaluating early degenerative …

Delayed gadolinium-enhanced MR to determine glycosaminoglycan concentration in reparative cartilage after autologous chondrocyte implantation: preliminary …

A Watanabe, Y Wada, T Obata, T Ueda, M Tamura… - Radiology, 2006 - pubs.rsna.org
Purpose: To prospectively evaluate delayed gadolinium-enhanced magnetic resonance (MR)
imaging of cartilage for assessment of glycosaminoglycan (GAG) concentration in …

Effects of chewing in working memory processing

Y Hirano, T Obata, K Kashikura, H Nonaka… - Neuroscience …, 2008 - Elsevier
It has been generally suggested that chewing produces an enhancing effect on cognitive
performance-related aspects of memory by the test battery. Furthermore, recent studies have …

Effects of chewing on cognitive processing speed

Y Hirano, T Obata, H Takahashi, A Tachibana… - Brain and …, 2013 - Elsevier
In recent years, chewing has been discussed as producing effects of maintaining and
sustaining cognitive performance. We have reported that chewing may improve or recover the …