[HTML][HTML] Subgroup-specific structural variation across 1,000 medulloblastoma genomes
…, A Klekner, TE Van Meter, T Kumabe, T Tominaga… - Nature, 2012 - nature.com
Medulloblastoma, the most common malignant paediatric brain tumour, is currently treated
with nonspecific cytotoxic therapies including surgery, whole-brain radiation, and aggressive …
with nonspecific cytotoxic therapies including surgery, whole-brain radiation, and aggressive …
[HTML][HTML] A genome-wide association study identifies RNF213 as the first Moyamoya disease gene
…, Y Suzuki, A Hata, S Tsuchiya, T Tominaga… - Journal of human …, 2011 - nature.com
Moyamoya disease (MMD) shows progressive cerebral angiopathy characterized by bilateral
internal carotid artery stenosis and abnormal collateral vessels. Although∼ 15% of MMD …
internal carotid artery stenosis and abnormal collateral vessels. Although∼ 15% of MMD …
Divergent clonal selection dominates medulloblastoma at recurrence
…, DW Fults, AW Walter, T Kumabe, T Tominaga… - Nature, 2016 - nature.com
The development of targeted anti-cancer therapies through the study of cancer genomes is
intended to increase survival rates and decrease treatment-related toxicity. We treated a …
intended to increase survival rates and decrease treatment-related toxicity. We treated a …
Effects of extracranial–intracranial bypass for patients with hemorrhagic moyamoya disease: results of the Japan Adult Moyamoya Trial
…, N Hashimoto, Y Okada, I Tsuji, T Tominaga… - Stroke, 2014 - Am Heart Assoc
Background and Purpose— About one half of those who develop adult-onset moyamoya
disease experience intracranial hemorrhage. Despite the extremely high frequency of …
disease experience intracranial hemorrhage. Despite the extremely high frequency of …
Mechanisms of primary blast-induced traumatic brain injury: insights from shock-wave research
…, H Yamamoto, K Takayama, T Tominaga - Journal of …, 2011 - liebertpub.com
Traumatic brain injury caused by explosive or blast events is traditionally divided into four
phases: primary, secondary, tertiary, and quaternary blast injury. These phases of blast-…
phases: primary, secondary, tertiary, and quaternary blast injury. These phases of blast-…
Cytogenetic prognostication within medulloblastoma subgroups
…, U Schüller, L Kren, T Kumabe, T Tominaga… - Journal of clinical …, 2014 - ascopubs.org
Purpose Medulloblastoma comprises four distinct molecular subgroups: WNT, SHH, Group 3,
and Group 4. Current medulloblastoma protocols stratify patients based on clinical features…
and Group 4. Current medulloblastoma protocols stratify patients based on clinical features…
Prognostic value of medulloblastoma extent of resection after accounting for molecular subgroup: a retrospective integrated clinical and molecular analysis
…, KKW Li, HK Ng, Y Yao, T Kumabe, T Tominaga… - The lancet …, 2016 - thelancet.com
Background Patients with incomplete surgical resection of medulloblastoma are controversially
regarded as having a marker of high-risk disease, which leads to patients undergoing …
regarded as having a marker of high-risk disease, which leads to patients undergoing …
The Tohoku medical megabank project: design and mission
…, S Ogishima, T Takai-Igarashi, T Tominaga… - Journal of …, 2016 - jstage.jst.go.jp
The Great East Japan Earthquake (GEJE) and resulting tsunami of March 11, 2011 gave
rise to devastating damage on the Pacific coast of the Tohoku region. The Tohoku Medical …
rise to devastating damage on the Pacific coast of the Tohoku region. The Tohoku Medical …
A proposed parent vessel geometry—based categorization of saccular intracranial aneurysms: computational flow dynamics analysis of the risk factors for lesion …
…, Y Matsumoto, K Takayama, T Tominaga… - Journal of …, 2005 - thejns.org
Object. The authors created a simple, broadly applicable classification of saccular
intracranial aneurysms into three categories: sidewall (SW), sidewall with branching vessel (SWBV), …
intracranial aneurysms into three categories: sidewall (SW), sidewall with branching vessel (SWBV), …
2021 Japanese guidelines for the management of Moyamoya disease: guidelines from the research committee on Moyamoya disease and Japan stroke society
M Fujimura, T Tominaga, S Kuroda… - Neurologia medico …, 2022 - jstage.jst.go.jp
… Cerebrovasc Dis 47: 178-187, 2019 36) Fujimura M, Inoue T, Shimizu H, Saito A, Mugikura
S, Tominaga T: Efficacy of prophylactic blood pressure lowering according to a standardized …
S, Tominaga T: Efficacy of prophylactic blood pressure lowering according to a standardized …