User profiles for Thomas W. Bouldin

Thomas W. Bouldin

Professor Emeritus of Pathology and Laboratory Medicine
Verified email at med.unc.edu
Cited by 4022

Intrathecal Gene Therapy for Giant Axonal Neuropathy

…, L Charnas, JE Hooper, TW Bouldin… - … England Journal of …, 2024 - Mass Medical Soc
Background Giant axonal neuropathy is a rare, autosomal recessive, pediatric, polysymptomatic,
neurodegenerative disorder caused by biallelic loss-of-function variants in GAN, the …

Clinical role of proton magnetic resonance spectroscopy in oncology: brain, breast, and prostate cancer

…, MG Ewend, F Collichio, DE Morris, TW Bouldin… - The lancet …, 2006 - thelancet.com
Standardised proton magnetic resonance spectroscopic imaging (MRSI) was initially
developed for routine in-situ clinical assessment of human brain tumours, and its use was later …

Pathogenesis of trimethyltin neuronal toxicity. Ultrastructural and cytochemical observations.

TW Bouldin, ND Goines, RC Bagnell… - The American Journal …, 1981 - ncbi.nlm.nih.gov
The ultrastructural cytopathologic and cytochemical effects of trimethyltin (TMT) neurotoxicity
were delineated in hippocampal and pyriform neurons of acutely intoxicated adult rats. TMT …

Septal dysembryoplastic neuroepithelial tumor: a comprehensive clinical, imaging, histopathologic, and molecular analysis

…, JT Boyd, J Chen, JC Corbo, TW Bouldin… - Neuro …, 2019 - academic.oup.com
Background Dysembryoplastic neuroepithelial tumors (DNETs) are uncommon neural
tumors presenting most often in children and young adults and associated with intractable …

A case of progressive multifocal leukoencephalopathy in a patient treated with infliximab

D Kumar, TW Bouldin, RG Berger - Arthritis & Rheumatism, 2010 - Wiley Online Library
We describe a 72‐year‐old white man with erosive rheumatoid arthritis in whom subacute
neurologic and psychiatric symptoms developed after 3 years of treatment with infliximab, …

The expression of the SWI/SNF ATPase subunits BRG1 and BRM in normal human tissues

DN Reisman, J Sciarrotta, TW Bouldin… - Applied …, 2005 - journals.lww.com
SWI/SNF is a chromatin-remodeling complex important in gene regulation, cytokine responses,
tumorigenesis, differentiation, and development. As a multitude of signaling pathways …

Intestinal pseudo-obstruction as the presenting manifestation of small-cell carcinoma of the lung: a paraneoplastic neuropathy of the gastrointestinal tract

…, CR FLEMING, CE BELL, TW BOULDIN… - Annals of Internal …, 1983 - acpjournals.org
A 58-year-old woman who had presented with intestinal pseudo-obstruction died 9 months
later from rapidly progressive neurologic symptoms and autonomic insufficiency. Her gastric …

Clinical applications of proton MR spectroscopy in oncology

…, M Varia, D Morris, TW Bouldin - … in cancer research …, 2002 - journals.sagepub.com
Proton magnetic resonance spectroscopy (H1-MRS) has been increasingly receiving more
attention from radiologists, neurosurgeons, radiation and medical oncologists in the “in situ” …

Fate of myelin lipids during degeneration and regeneration of peripheral nerve: an autoradiographic study

…, T Earnhardt, N Goines, TW Bouldin - Journal of …, 1994 - Soc Neuroscience
Four weeks after labeling myelin lipids with an intraneural injection of 3H-acetate, sciatic
nerves were crushed, and the distribution of radiolabeled myelin lipids was followed by …

Immunobiology of primary intracranial tumors: Part 7: Active immunization of patients with anaplastic human glioma cells: a pilot study

…, LF Dudka, PR Wilds, DH Williams, TW Bouldin… - Journal of …, 1983 - thejns.org
✓ Twenty patients with malignant gliomas were selected for active immunization within 4
weeks following surgery. Each patient had a Karnofsky Functional Rating equal to or greater …