[HTML][HTML] Transcription factor Runx2 is a regulator of epithelial–mesenchymal transition and invasion in thyroid carcinomas
Runx2/Cbfa1 is a member of the Runt-related transcription factor family and is an essential
regulator of osteoblast/chondrocyte differentiation. Recently, aberrant expression of Runx2 …
regulator of osteoblast/chondrocyte differentiation. Recently, aberrant expression of Runx2 …
Hypoxia-inducible adenosine A2B receptor modulates proliferation of colon carcinoma cells
…, T Nakazawa, DF Niu, K Mochizuki, T Kawasaki… - Human pathology, 2010 - Elsevier
Extracellular adenosine regulates a wide variety of physiological processes by interacting
with 4 adenosine receptor subtypes: A1, A2A, A2B, and A3. However, little is known of their …
with 4 adenosine receptor subtypes: A1, A2A, A2B, and A3. However, little is known of their …
[HTML][HTML] TIGIT/CD155 axis mediates resistance to immunotherapy in patients with melanoma with the inflamed tumor microenvironment
…, Y Umeda, Y Nakamura, T Kawasaki… - … for immunotherapy of …, 2021 - ncbi.nlm.nih.gov
Background Patients with cancer benefit from treatment with immune checkpoint inhibitors (ICIs),
and those with an inflamed tumor microenvironment (TME) and/or high tumor mutation …
and those with an inflamed tumor microenvironment (TME) and/or high tumor mutation …
[HTML][HTML] Epigenetic silencing of TTF-1/NKX2-1 through DNA hypermethylation and histone H3 modulation in thyroid carcinomas
…, D Ma, D Niu, K Mochizuki, T Kawasaki… - Laboratory …, 2009 - nature.com
Thyroid transcription factor-1 (TTF-1), also known as NKX2-1, is a homeodomain containing
transcriptional factor identified in thyroid, lung and central nervous system. In the thyroid, TTF…
transcriptional factor identified in thyroid, lung and central nervous system. In the thyroid, TTF…
Global histone modification of histone H3 in colorectal cancer and its precursor lesions
…, T Kondo, D Ma, D Niu, K Mochizuki, T Kawasaki… - Human pathology, 2012 - Elsevier
Chromatin remodeling through histone modification is an important mechanism of epigenetic
gene dysregulation in human cancers. However, little is known about global alteration of …
gene dysregulation in human cancers. However, little is known about global alteration of …
Expression of MHC Class I on breast cancer cells correlates inversely with HER2 expression
…, Y Kawaguchi, S Inoue, T Kawasaki… - …, 2012 - Taylor & Francis
HER2 is a promising target for immunotherapeutic interventions with T cell-based approaches
since it is amplified and overexpressed in 20–30% of breast cancers. However, several …
since it is amplified and overexpressed in 20–30% of breast cancers. However, several …
[HTML][HTML] EHF suppresses cancer progression by inhibiting ETS1-mediated ZEB expression
…, T Kawataki, K Miyake, H Ishii, T Kawasaki… - Oncogenesis, 2021 - nature.com
ETS homologous factor (EHF) belongs to the epithelium-specific subfamily of the E26
transformation-specific (ETS) transcription factor family. Currently, little is known about EHF’s …
transformation-specific (ETS) transcription factor family. Currently, little is known about EHF’s …
Diagnostic performance of on-site computed CT-fractional flow reserve based on fluid structure interactions: comparison with invasive fractional flow reserve and …
S Fujimoto, T Kawasaki, KK Kumamaru… - European Heart …, 2019 - academic.oup.com
Aims We evaluated diagnostic accuracy of CT-fractional flow reserve (CT-FFR) computed on-site
with a new vendor workstation, against invasive FFR as the reference standard. …
with a new vendor workstation, against invasive FFR as the reference standard. …
Identification of integrin α3 as a molecular marker of cells undergoing epithelial–mesenchymal transition and of cancer cells with aggressive phenotypes
T Shirakihara, T Kawasaki, A Fukagawa… - Cancer …, 2013 - Wiley Online Library
Epithelial–mesenchymal transition ( EMT ) is a crucial event in wound healing, tissue repair,
and cancer progression in adult tissues. Transforming growth factor ( TGF )‐β induces EMT …
and cancer progression in adult tissues. Transforming growth factor ( TGF )‐β induces EMT …
RET rearrangements and BRAF mutation in undifferentiated thyroid carcinomas having papillary carcinoma components
…, T Nakazawa, M Iwashina, T Kawasaki… - …, 2010 - Wiley Online Library
Mochizuki K, Kondo T, Nakazawa T, Iwashina M, Kawasaki T, Nakamura N, Yamane T, Murata
S‐i, Ito K, Kameyama K, Kobayashi M & Katoh R (2010) Histopathology 57, 444–450 RET …
S‐i, Ito K, Kameyama K, Kobayashi M & Katoh R (2010) Histopathology 57, 444–450 RET …
