Comparison of longitudinal metabolite relaxation times in different regions of the human brain at 1.5 and 3 Tesla

T Ethofer, I Mader, U Seeger, G Helms… - … in Medicine: An …, 2003 - Wiley Online Library
In vivo longitudinal relaxation times of N‐acetyl compounds (NA), choline‐containing substances
(Cho), creatine (Cr), myo‐inositol (mI), and tissue water were measured at 1.5 and 3 T …

Parameterized evaluation of macromolecules and lipids in proton MR spectroscopy of brain diseases

U Seeger, U Klose, I Mader, W Grodd… - … in Medicine: An …, 2003 - Wiley Online Library
Short echo time (TE) proton MR spectra of the brain include signals of several metabolites
as well as macromolecules. In various pathologies, such as brain tumors and multiple …

MR Imaging and 1H Spectroscopy of Brain Metabolites in Hepatic Encephalopathy: Time-Course of Renormalization after Liver Transplantation1

T Naegele, W Grodd, R Viebahn, U Seeger, U Klose… - Radiology, 2000 - pubs.rsna.org
PURPOSE: To evaluate changes in hydrogen 1 magnetic resonance (MR) spectroscopic
findings in overt or subclinical hepatic encephalopathy (HE) after liver transplantation and to …

Proton magnetic resonance spectroscopy with metabolite nulling reveals regional differences of macromolecules in normal human brain

I Mader, U Seeger, J Karitzky, M Erb… - Journal of Magnetic …, 2002 - Wiley Online Library
Purpose To quantify the macromolecular content in different anatomic brain regions and to
evaluate an age dependency of the macromolecular concentrations. Material and Methods A …

Localized proton magnetic resonance spectroscopy of the cerebellum in detoxifying alcoholics

D Seitz, U Widmann, U Seeger… - Alcoholism: Clinical …, 1999 - Wiley Online Library
An increased daily alcohol consumption results in neurological symptoms and morphological
central nervous system changes, eg shrinkage of the frontal lobes and the cerebellar …

Reliable detection of macromolecules in single‐volume 1H NMR spectra of the human brain

U Seeger, I Mader, T Nägele, W Grodd… - … in Medicine: An …, 2001 - Wiley Online Library
In short echo time proton MR spectra of the brain, resonances from macromolecules are
visible. The macromolecular resonances in the 0.5–2.0 ppm region can be affected by lipid …

MR imaging and localized proton MR spectroscopy in late infantile neuronal ceroid lipofuscinosis.

…, W Grodd, A Schwab, U Seeger… - American journal …, 1998 - Am Soc Neuroradiology
PURPOSE Late juvenile neuronal ceroid lipofuscinosis (NCL) is a lysosomal neurodegenerative
disorder caused by the accumulation of lipopigment in neurons. Our purpose was to …

Proton MRS in Kennedy disease: absolute metabolite and macromolecular concentrations

I Mader, J Karitzky, U Klose, U Seeger… - Journal of Magnetic …, 2002 - Wiley Online Library
Purpose To investigate whether glutamine and glutamate (Glx) were elevated in Kennedy
Disease (KD), and whether pathological proteins were spectroscopically visible as altered …

MR imaging and spectroscopy of a tuber cinereum hamartoma in a patient with growth hormone deficiency and hypogonadotropic hypogonadism

DD Martin, U Seeger, MB Ranke… - American journal of …, 2003 - Am Soc Neuroradiology
To our knowledge, this is the first report of hypogonadotropic hypogonadism, or growth
hormone deficiency, in a patient without non-Pallister-Hall syndrome who had hypothalamic …

Proton spectroscopy of human brain with very short echo time using high gradient amplitudes

U Seeger, U Klose, D Seitz, T Nägele, O Lutz… - Magnetic resonance …, 1998 - Elsevier
In localized proton magnetic resonance spectroscopy very short echo times (TE) are
achieved to diminish signal loss due to T 2 relaxation and to avoid phase distortions due to J-…