Stroke is the second leading cause of death and the third leading cause of disability worldwide
and its burden is increasing rapidly in low-income and middle-income countries, many of …

Background Among patients with atrial fibrillation, the risk of stroke is highest for those with
a history of stroke; however, oral anticoagulants can lower the risk of recurrent stroke by two-…

Cognitive impairment associated with aging has emerged as one of the major public health
challenges of our time. Although Alzheimer’s disease is the leading cause of clinically …

Our objectives were to investigate the utility of the Hachinski Ischemic Score (HIS) in differentiating
patients with pathologically verified Alzheimer's disease (AD), multi-infarct dementia (…

Cerebral small vessel disease (SVD) is a common accompaniment of ageing. Features
seen on neuroimaging include recent small subcortical infarcts, lacunes, white matter …

• Twenty-four patients of comparable age, blood pressure, and degree of dementia were
classified by an "Ischemic Score" based on clinical features into "multi-infarct" and "primary …

Background Previous studies have shown that carotid endarterectomy in patients with
symptomatic severe carotid stenosis (defined as stenosis of 70 to 99 percent of the luminal …

Background and Purpose— One in 3 individuals will experience a stroke, dementia or both.
Moreover, twice as many individuals will have cognitive impairment short of dementia as …

The typical, insidious, slowly progressive dementia of old age (primary senile dementia) is
not due to atherosclerosis. Most cases show Alzheimer-like degeneration of the brain at …

Background The number of individuals living with dementia is increasing, negatively affecting
families, communities, and health-care systems around the world. A successful response …