Background Interferon beta reduces activity in multiple sclerosis as measured clinically and
by magnetic resonance imaging (MRI). We assessed the effect of interferon beta-1a on the …

Using the ImmunoChip custom genotyping array, we analyzed 14,498 subjects with multiple
sclerosis and 24,091 healthy controls for 161,311 autosomal variants and identified 135 …

Objectives: To evaluate the clinical characteristics, course and prognosis of Devic’s neuromyelitis
optica (DNO), to evaluate the prognostic role of demographic and clinical features, to …

Background and objective: We explored which clinical and biochemical variables predict
conversion from clinically isolated syndrome (CIS) to clinically definite multiple sclerosis (CDMS…

Objective: Microvesicles (MVs) have been indicated as important mediators of intercellular
communication and are emerging as new biomarkers of tissue damage. Our previous data …

T helper 17 (T H 17) cells are key players in multiple sclerosis (MS), and studies in animal
models demonstrated that effector T H 17 cells that trigger brain autoimmunity originate in the …

Background Movement-associated cortical reorganisation is known to occur in multiple sclerosis
(MS). We aimed to define the development of such cortical reorganisation by comparing …

To assess regional grey matter (GM) changes in a large cohort of multiple sclerosis (MS)
patients with different clinical phenotypes, using voxel-based morphometry (VBM) and their …

Previous studies assessing the magnetic resonance imaging (MRI) correlates of cognitive
dysfunction in multiple sclerosis (MS) achieved conflicting results. Diffusion tensor (DT)-MRI …

Objectives In multiple sclerosis (MS), magnetic resonance imaging (MRI) is a sensitive tool
for detecting white matter lesions, but its diagnostic specificity is still suboptimal; ambiguous …