Diagnosis and treatment of fetal cardiac disease: a scientific statement from the American Heart Association
…, TL Spray, JF Strasburger, W Tworetzky… - Circulation, 2014 - Am Heart Assoc
Background— The goal of this statement is to review available literature and to put forth a
scientific statement on the current practice of fetal cardiac medicine, including the diagnosis …
scientific statement on the current practice of fetal cardiac medicine, including the diagnosis …
Hypoplastic left heart syndrome: current considerations and expectations
…, NS Ghanayem, JP Cheatham, W Tworetzky… - Journal of the American …, 2012 - jacc.org
In the recent era, no congenital heart defect has undergone a more dramatic change in
diagnostic approach, management, and outcomes than hypoplastic left heart syndrome (HLHS). …
diagnostic approach, management, and outcomes than hypoplastic left heart syndrome (HLHS). …
Current status of fetal cardiac intervention
DB McElhinney, W Tworetzky, JE Lock - Circulation, 2010 - Am Heart Assoc
… 8 Selamet Tierney ES, Wald RM, McElhinney DB, Marshall AC, Benson CB, Marcus EN,
Marx GR, Levine JC, Wilkins-Haug L, Lock JE, Tworetzky W. Changes in left heart …
Marx GR, Levine JC, Wilkins-Haug L, Lock JE, Tworetzky W. Changes in left heart …
Brain volume and metabolism in fetuses with congenital heart disease: evaluation with quantitative magnetic resonance imaging and spectroscopy
C Limperopoulos, W Tworetzky, DB McElhinney… - Circulation, 2010 - Am Heart Assoc
Background— Adverse neurodevelopmental outcome is an important source of morbidity in
children with congenital heart disease (CHD). A significant proportion of newborns with …
children with congenital heart disease (CHD). A significant proportion of newborns with …
Improved surgical outcome after fetal diagnosis of hypoplastic left heart syndrome
W Tworetzky, DB McElhinney, VM Reddy, MM Brook… - Circulation, 2001 - Am Heart Assoc
Background—Hypoplastic left heart syndrome (HLHS) is frequently diagnosed prenatally,
but this has not been shown to improve surgical outcome. Methods and Results—We …
but this has not been shown to improve surgical outcome. Methods and Results—We …
Balloon dilation of severe aortic stenosis in the fetus: potential for prevention of hypoplastic left heart syndrome: candidate selection, technique, and results of …
W Tworetzky, L Wilkins-Haug, RW Jennings… - Circulation, 2004 - Am Heart Assoc
Background— Preventing the progression of fetal aortic stenosis (AS) to hypoplastic left heart
syndrome (HLHS) requires identification of fetuses with salvageable left hearts who would …
syndrome (HLHS) requires identification of fetuses with salvageable left hearts who would …
Delayed cortical development in fetuses with complex congenital heart disease
…, AJ Du Plessis, M Bouyssi-Kobar, W Tworetzky… - Cerebral …, 2013 - academic.oup.com
Neurologic impairment is a major complication of complex congenital heart disease (CHD).
A growing body of evidence suggests that neurologic dysfunction may be present in a …
A growing body of evidence suggests that neurologic dysfunction may be present in a …
Predictors of technical success and postnatal biventricular outcome after in utero aortic valvuloplasty for aortic stenosis with evolving hypoplastic left heart syndrome
…, GR Marx, A Mizrahi-Arnaud, JE Lock, W Tworetzky - Circulation, 2009 - Am Heart Assoc
Background— Aortic stenosis in the midgestation fetus with a normal-sized or dilated left
ventricle predictably progresses to hypoplastic left heart syndrome when associated with …
ventricle predictably progresses to hypoplastic left heart syndrome when associated with …
Fetal aortic valve stenosis and the evolution of hypoplastic left heart syndrome: patient selection for fetal intervention
…, AC Marshall, JE Lock, EN Marcus, W Tworetzky - Circulation, 2006 - Am Heart Assoc
Background— Fetal aortic valvuloplasty may prevent progression of aortic stenosis (AS) to
hypoplastic left heart syndrome (HLHS). Predicting which fetuses with AS will develop HLHS …
hypoplastic left heart syndrome (HLHS). Predicting which fetuses with AS will develop HLHS …
Creation of an atrial septal defect in utero for fetuses with hypoplastic left heart syndrome and intact or highly restrictive atrial septum
AC Marshall, ME van der Velde, W Tworetzky… - Circulation, 2004 - Am Heart Assoc
Background— Infants born with hypoplastic left heart syndrome and an intact or highly
restrictive atrial septum face a neonatal mortality of at least 48% despite early postnatal left atrial …
restrictive atrial septum face a neonatal mortality of at least 48% despite early postnatal left atrial …