User profiles for W.R. Witschey

Walter Witschey

Associate Professor of Radiology, University of Pennsylvania
Verified email at pennmedicine.upenn.edu
Cited by 3939

Machine learning in cardiovascular flows modeling: Predicting arterial blood pressure from non-invasive 4D flow MRI data using physics-informed neural networks

G Kissas, Y Yang, E Hwuang, WR Witschey… - Computer Methods in …, 2020 - Elsevier
Advances in computational science offer a principled pipeline for predictive modeling of
cardiovascular flows and aspire to provide a valuable tool for monitoring, diagnostics and …

A multiancestry genome-wide association study of unexplained chronic ALT elevation as a proxy for nonalcoholic fatty liver disease with histological and radiological …

…, DE Kaplan, ME Haas, MT MacLean, WR Witschey… - Nature …, 2022 - nature.com
Nonalcoholic fatty liver disease (NAFLD) is a growing cause of chronic liver disease. Using
a proxy NAFLD definition of chronic elevation of alanine aminotransferase (cALT) levels …

Sodium MR imaging detection of mild Alzheimer disease: preliminary study

…, CM Clark, MA Elliott, WR Witschey… - American Journal …, 2009 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: There is significant interest in the development of novel
noninvasive techniques for the diagnosis of Alzheimer disease (AD) and tracking its …

MR intracranial vessel wall imaging: a systematic review

…, MD Schnall, JE Kirsch, WR Witschey… - Journal of …, 2020 - Wiley Online Library
The purpose of this systematic review is to identify trends and extent of variability in intracranial
vessel wall MR imaging (VWI) techniques and protocols. Although variability in selection …

Iron imaging in myocardial infarction reperfusion injury

…, A Gulhane, H Litt, W Matthai, WR Witschey - Nature …, 2020 - nature.com
Restoration of coronary blood flow after a heart attack can cause reperfusion injury potentially
leading to impaired cardiac function, adverse tissue remodeling and heart failure. Iron is …

Noninvasive assessment of lipomatous metaplasia as a substrate for ventricular tachycardia in chronic infarct

L Xu, B Desjardins, WR Witschey… - Circulation …, 2023 - Am Heart Assoc
Myocardial lipomatous metaplasia (LM) has been increasingly reported in patients with
prior myocardial infarction. Cardiac magnetic resonance and cardiac contrast-enhanced …

Single‐Voxel 1H MR spectroscopy of cerebral nicotinamide adenine dinucleotide (NAD+) in humans at 7T using a 32‐channel volume coil

…, JA Baur, FM Marincola, WR Witschey… - Magnetic resonance …, 2020 - Wiley Online Library
Purpose Reliable monitoring of tissue nicotinamide adenine dinucleotide (NAD + ) concentration
may provide insights on its roles in normal and pathological aging. In the present study, …

Strategies for Implementing Machine Learning Algorithms in the Clinical Practice of Radiology

…, MD Ritchie, D Rader, CE Kahn, WR Witschey… - Radiology, 2024 - pubs.rsna.org
Despite recent advancements in machine learning (ML) applications in health care, there
have been few benefits and improvements to clinical medicine in the hospital setting. To …

Isosorbide dinitrate, with or without hydralazine, does not reduce wave reflections, left ventricular hypertrophy, or myocardial fibrosis in patients with heart failure with …

…, J Chittams, RR Townsend, WR Witschey… - Journal of the …, 2017 - Am Heart Assoc
Background Wave reflections, which are increased in patients with heart failure with preserved
ejection fraction, impair diastolic function and promote pathologic myocardial remodeling. …

Nanodisco Balls: Control over Surface versus Core Loading of Diagnostically Active Nanocrystals into Polymer Nanoparticles

…, T Paik, JL Nichol, Z Tian, PC Naha, WR Witschey… - ACS …, 2014 - ACS Publications
Nanoparticles of complex architectures can have unique properties. Self-assembly of
spherical nanocrystals is a high yielding route to such systems. In this study, we report the self-…