Zero-order controlled-release polymer matrices for micro-and macromolecules

DST Hsieh, WD Rhine, R Langer - Journal of pharmaceutical sciences, 1983 - Elsevier
Theoretical and experimental analyses demonstrate that a hemispheric polymer–drug matrix
laminated with an impermeable coating, except for an exposed cavity in the center face, …

A quality improvement project to increase breast milk use in very low birth weight infants

…, TA Hanson-Timpson, CC Nisbet, WD Rhine… - …, 2012 - publications.aap.org
OBJECTIVE: To evaluate a multihospital collaborative designed to increase breast milk
feeding in premature infants. METHODS: Eleven NICUs in the California Perinatal Quality of …

Polymers for sustained macromolecule release: procedures to fabricate reproducible delivery systems and control release kinetics

WD Rhine, DST Hsieh, R Langer - Journal of pharmaceutical …, 1980 - Wiley Online Library
Matrixes composed of ethylene–vinyl acetate copolymer are useful vehicles for the sustained
release of macromolecules such as proteins. A new procedure for fabricating these …

Sonography, CT, and MR imaging: a prospective comparison of neonates with suspected intracranial ischemia and hemorrhage

…, P Bracci, HE D'Arceuil, WD Rhine… - American journal …, 2000 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Sonography, CT, and MR imaging are commonly used to
screen for neonatal intracranial ischemia and hemorrhage, yet few studies have attempted to …

Decreased use of neonatal extracorporeal membrane oxygenation (ECMO): how new treatment modalities have affected ECMO utilization

SR Hintz, DM Suttner, AM Sheehan, WD Rhine… - …, 2000 - publications.aap.org
Objective: Over the last decade, several new therapies, including high-frequency oscillatory
ventilation (HFOV), exogenous surfactant therapy, and inhaled nitric oxide (iNO), have …

Venoarterial versus venovenous extracorporeal membrane oxygenation in congenital diaphragmatic hernia: the Extracorporeal Life Support Organization Registry …

RA Dimmitt, RL Moss, WD Rhine, WE Benitz… - Journal of pediatric …, 2001 - Elsevier
Background/Purpose: Venoarterial (VA) extracorporeal membrane oxygenation (ECMO)
traditionally has been the mode of support used in congenital diaphragmatic hernia (CDH). A …

A new approach to achieve zero-order release kinetics from diffusion-controlled polymer matrix systems

WD Rhine, V Sukhatme, DST Hsieh… - Controlled release of …, 1980 - books.google.com
Matrix devices as vehicles for drug delivery have advan—tages in their ease of fabrication
when compared to other sustained release systems such as membrane—encapsulated res—…

Brainstem bilirubin toxicity in the newborn primate may be promoted and reversed by modulating PCO2

…, SM Gospe, WD Rhine, M Seyal, D Saeed… - Pediatric …, 1993 - nature.com
ABSTRACT: The auditory brainstem response (ABR) was monitored during infusion of bilirubin
in six ventilated newborn rhesus monkeys (138–145 d gestation) while acute changes in …

Bilirubin toxicity and differentiation of cultured astrocytes

WD Rhine, SP Schmitter, ACH Yu, LF Eng… - Journal of …, 1999 - nature.com
OBJECTIVE: To study the toxicity of bilirubin in primary cultures of newborn rat cerebral cortical
astrocytes. STUDY DESIGN: Primary cultures of newborn rat astrocytes were incubated …

[HTML][HTML] An analysis of time to improvement in oxygenation in Japanese preterm and late preterm or term neonates with hypoxic respiratory failure and pulmonary …

WD Rhine, S Suzuki, JL Potenziano, S Escalante… - Clinical Therapeutics, 2019 - Elsevier
Purpose We analyzed data from an ongoing registry to determine time to improvement in
oxygenation in preterm and late preterm or term neonates with hypoxic respiratory failure and …