User profiles for William Kelly
William G. KellyEmory University Biology Department Verified email at emory.edu Cited by 8206 |
[HTML][HTML] Design and end points of clinical trials for patients with progressive prostate cancer and castrate levels of testosterone: recommendations of the Prostate …
…, D Petrylak, P Kantoff, E Basch, WK Kelly… - Journal of clinical …, 2008 - ncbi.nlm.nih.gov
… Recommendations will evolve as data are generated on the utility of intermediate end …
databases that will allow validation or refinement of the intermediate end points proposed herein. …
databases that will allow validation or refinement of the intermediate end points proposed herein. …
Histone deacetylases and cancer: causes and therapies
…, VM Richon, R Breslow, T Miller, WK Kelly - Nature Reviews …, 2001 - nature.com
Together, histone acetyltransferases and histone deacetylases (HDACs) determine the
acetylation status of histones. This acetylation affects the regulation of gene expression, and …
acetylation status of histones. This acetylation affects the regulation of gene expression, and …
[HTML][HTML] The rde-1 gene, RNA interference, and transposon silencing in C. elegans
Double-stranded (ds) RNA can induce sequence-specific inhibition of gene function in several
organisms. However, both the mechanism and the physiological role of the interference …
organisms. However, both the mechanism and the physiological role of the interference …
Phase I study of an oral histone deacetylase inhibitor, suberoylanilide hydroxamic acid, in patients with advanced cancer
WK Kelly, OA O'Connor, LM Krug, JH Chiao… - Journal of clinical …, 2005 - ascopubs.org
Purpose To determine the safety, dosing schedules, pharmacokinetic profile, and biologic
effect of orally administered histone deacetylase inhibitor suberoylanilide hydroxamic acid (…
effect of orally administered histone deacetylase inhibitor suberoylanilide hydroxamic acid (…
Histone deacetylase inhibitors.
…, VM Richon, T Miller, WK Kelly - Advances in cancer …, 2004 - europepmc.org
The base sequence of DNA provides the genetic code for proteins. The regulation of
expression or suppression of gene transcription is largely determined by the structure of the …
expression or suppression of gene transcription is largely determined by the structure of the …
Veterinary clinical diagnosis.
WR Kelly - Veterinary clinical diagnosis., 1967 - cabdirect.org
This is a new book, intended primarily for veterinary students. Its concise form and excellent
photographs should commend it to them; and others will also find it useful. The subject is …
photographs should commend it to them; and others will also find it useful. The subject is …
Distinct Requirements for Somatic and Germline Expression of a Generally Expressed Caernorhabditis elegans Gene
WG Kelly, SQ Xu, MK Montgomery, A Fire - Genetics, 1997 - academic.oup.com
In screening for embryonic-lethal mutations in Caernorhabditis elegans, we defined an
essential gene (let-858) that encodes a nuclear protein rich in acidic and basic residues. We …
essential gene (let-858) that encodes a nuclear protein rich in acidic and basic residues. We …
RNA polymerase II is a glycoprotein. Modification of the COOH-terminal domain by O-GlcNAc
The largest subunit of mammalian RNA polymerase II (RNAP II) contains at its carboxyl terminus
an unusual domain consisting of 52 tandem repeats of the consensus sequence Tyr-Ser…
an unusual domain consisting of 52 tandem repeats of the consensus sequence Tyr-Ser…
[HTML][HTML] Lactobacillus plantarum MB452 enhances the function of the intestinal barrier by increasing the expression levels of genes involved in tight junction formation
Background Intestinal barrier function is important for preserving health, as a compromised
barrier allows antigen entry and can induce inflammatory diseases. Probiotic bacteria can …
barrier allows antigen entry and can induce inflammatory diseases. Probiotic bacteria can …
[HTML][HTML] Randomized, double-blind, placebo-controlled phase III trial comparing docetaxel and prednisone with or without bevacizumab in men with metastatic …
Purpose A randomized, placebo-controlled study based on preclinical and clinical data that
supports the potential role of vascular endothelial growth factor in prostate cancer was …
supports the potential role of vascular endothelial growth factor in prostate cancer was …