Neurexins are neuronal cell surface proteins with hundreds of isoforms generated by alternative
splicing. Here we describe neuroligin 1, a neuronal cell surface protein that is enriched …

178 Hata and Nakajima years). Total cholesterol was lower by a mean of 10 mg/dl (0.26
mmol/L) in fishing villages than in cities, and triglycerides lower by a mean of 15 mg/dl (0.17 …

The Hippo pathway was discovered as a signal transduction pathway that regulates organ
size in Drosophila melanogaster. It is composed of three components: cell surface upstream …

The genome of Aspergillus oryzae, a fungus important for the production of traditional
fermented foods and beverages in Japan, has been sequenced. The ability to secrete large …

Two new screening scales for psychological distress, the K6 and K10, have been developed
using the item response theory and shown to outperform existing screeners in English. We …

PSD-95 is a component of postsynaptic densities in central synapses. It contains three PDZ
domains that localizeN-methyl-d-aspartate receptor subunit 2 (NMDA2 receptor) and K + …

Importance Very short mandatory dual antiplatelet therapy (DAPT) after percutaneous coronary
intervention (PCI) with a drug-eluting stent may be an attractive option. Objective To test …

Clostridial neurotoxins inhibit neurotransmitter release by selective and specific intracellular
proteolysis of synaptobrevin/VAMP, synaptosomal‐associated protein of 25 kDa (SNAP‐25) …

THREE synaptic proteins, syntaxin, SNAP-25 and synaptobrevin, were recently identified as
targets of clostridial neurotoxins that irreversibly inhibit synaptic vesicle fusion 1–4 . …

A placebo-controlled study was conducted to test the effect of Calpis (Calpis Food Industry
Co, Ltd, Tokyo, Japan) sour milk, ie, a milk fermented with a starter containing Lactobacillus …