User profiles for Y. Kai

Yan KAI

Dana-Farber Cancer Institute, Harvard University
Verified email at jimmy.harvard.edu
Cited by 920

PHOSPHOENOLPYRUVATE CARBOXYLASE: A New Era of Structural Biology

K Izui, H Matsumura, T Furumoto, Y Kai - Annu. Rev. Plant Biol., 2004 - annualreviews.org
… Two students in Kai's laboratory brought about the long-awaited breakthrough. One of the
students unconsciously used an extraordinarily low-molecular weight polyethylene glycol (…

Biodegradation of gallotannins and ellagitannins

L Mingshu, Y Kai, H Qiang… - Journal of basic …, 2006 - Wiley Online Library
Nowadays, many researches have been made on gallotannin biodegradation and have
gained great success in further utilization. Some of industrial applications of these findings are …

Phosphoenolpyruvate carboxylase: three-dimensional structure and molecular mechanisms

Y Kai, H Matsumura, K Izui - Archives of Biochemistry and Biophysics, 2003 - Elsevier
Phosphoenolpyruvate carboxylase (PEPC; EC 4.1.1.31) catalyzes the irreversible carboxylation
of phosphoenolpyruvate (PEP) to form oxaloacetate and Pi using Mg 2+ or Mn 2+ as a …

[PDF][PDF] High-coverage whole-genome sequencing of the expanded 1000 Genomes Project cohort including 602 trios

…, Z Chong, Y Chen, X Yang, J Lin, MB Gerstein, Y Kai… - Cell, 2022 - cell.com
… Secondary y axis: % of autosomal phase 3 variants recalled in the high-coverage call set
across SNVs (A) and INDELs (B) in easy and difficult regions of the genome. See also Figure …

[HTML][HTML] Skeletal muscle Foxo1 (Fkhr) transgenic mice have less skeletal muscle mass, down-regulated type I (Slow twitch/red muscle) fiber genes, and impaired …

Y Kamei, S Miura, M Suzuki, Y Kai, J Mizukami… - Journal of Biological …, 2004 - ASBMB
FOXO1, a member of the FOXO forkhead type transcription factors, is markedly up-regulated
in skeletal muscle in energy-deprived states such as fasting and severe diabetes, but its …

Tumor necrosis factor and interleukin-1β: suppression of food intake by direct action in the central nervous system

CR Plata-Salamán, Y Oomura, Y Kai - Brain research, 1988 - Elsevier
Intracerebroventricular microinfusion of recombinant human tumor necrosis factor (rhTNF)
and recombinant human interleukin-1β (rhIL-1β) suppressed food intake in rats. Central …

Luminescent polymer containing the Eu (III) complex having fast radiation rate and high emission quantum efficiency

…, Y Wada, N Kanehisa, Y Kai… - The Journal of …, 2003 - ACS Publications
Radiation rates and emission quantum yields of Eu(III) were modified using asymmetric
deuterated Eu(III) complexes doped in poly(methyl methacrylate) (PMMA) deuterated tris-(…

[HTML][HTML] Social participation and the prevention of functional disability in older Japanese: the JAGES cohort study

S Kanamori, Y Kai, J Aida, K Kondo, I Kawachi, H Hirai… - PloS one, 2014 - journals.plos.org
Background We examined the relationship between incident functional disability and social
participation from the perspective of number of types of organizations participated in and …

Synergistic effects of (−)-epigallocatechin gallate with (−)-epicatechin, sulindac, or tamoxifen on cancer-preventive activity in the human lung cancercell line PC-9

M Suganuma, S Okabe, Y Kai, N Sueoka, E Sueoka… - Cancer Research, 1999 - AACR
The study on incorporation of [ 3 H](−)-epigallocatechin gallate (EGCG) into human lung cancer
cell line PC-9 indicated that the [ 3 H]EGCG incorporation was significantly enhanced by …

Propofol activates GABAA receptor-chloride ionophore complex in dissociated hippocampal pyramidal neurons of the rat.

M Hara, Y Kai, Y Ikemoto - Anesthesiology, 1993 - europepmc.org
Background The molecular mechanism of propofol anesthesia has been related to facilitation
of the inhibitory neurotransmission mediated by gamma-aminobutyric acid (GABA). In the …